Just looking at tobacco use from a hormonal perspective, it would seem to be favorable from Peat's perspective, no? In chronic users you have decreased prolactin, estrogen, parathyroid, IGF-1, etc. You even see increased thyroid and testosterone in some cases.
Under the Peat paradigm, could one not argue that the unfavorable change in catecholamine concentrations could be offset by pairing it with sugar and that many of the downsides associated with it could be due to increased substrate turnover and induced deficiencies from increased metabolism?
An example review paper:
http://eje-online.org/content/152/4/491.long
Under the Peat paradigm, could one not argue that the unfavorable change in catecholamine concentrations could be offset by pairing it with sugar and that many of the downsides associated with it could be due to increased substrate turnover and induced deficiencies from increased metabolism?
An example review paper:
http://eje-online.org/content/152/4/491.long