Is calcifediol better than cholecalciferol for vitamin D supplementation? - Osteoporosis International
"First, oral calcifediol results in a more rapid increase in serum 25OHD compared to oral cholecalciferol.
Second, oral calcifediol is more potent than cholecalciferol, so that lower dosages are needed.
Third, oral calcifediol has a higher rate of intestinal absorption and this may have important advantages in case of decreased intestinal absorption capacity due to a variety of diseases. A potential additional advantage of oral calcifediol is a linear dose-response curve, irrespective of baseline serum 25OHD, whereas the rise in serum 25OHD is lower after oral cholecalciferol, when baseline serum 25OHD is higher.
Finally, intermittent intake of calcifediol results in fairly stable serum 25OHD compared with greater fluctuations after intermittent oral cholecalciferol."
Found this from a new product by d.velop™ claims to be 3x more potent and more efficient than vitamin D3. Seems to make sense but I was curious because no one seems to talk about it.
"First, oral calcifediol results in a more rapid increase in serum 25OHD compared to oral cholecalciferol.
Second, oral calcifediol is more potent than cholecalciferol, so that lower dosages are needed.
Third, oral calcifediol has a higher rate of intestinal absorption and this may have important advantages in case of decreased intestinal absorption capacity due to a variety of diseases. A potential additional advantage of oral calcifediol is a linear dose-response curve, irrespective of baseline serum 25OHD, whereas the rise in serum 25OHD is lower after oral cholecalciferol, when baseline serum 25OHD is higher.
Finally, intermittent intake of calcifediol results in fairly stable serum 25OHD compared with greater fluctuations after intermittent oral cholecalciferol."
Found this from a new product by d.velop™ claims to be 3x more potent and more efficient than vitamin D3. Seems to make sense but I was curious because no one seems to talk about it.