Hi folks! I have some strong points against some of Rays ideas:
So all started because my blood lipid levels have gone bad from being spot on average before I started "peating". LDL is high now.
I was looking around once more and found quite shocking information. It is quite obvious and contradictory to things Ray said. I did my body wrong with all the coconut oil and butter rather than olive oil and fish. There's an effect just like Ray describes that harms the body through fatty acid composition for a long time, but it's not about PUFA but the most common SFA in dairy, palmitic acid - which is evil (see at the end).
A great summary and mountain of information can be found on
http://edubily.de/2014/10/fette-das-der ... n-teil-iv/
but it is in German.
I thought Ray said that babies are all created saturated - which of course would SFA seem quite optimal.
http://www.ncbi.nlm.nih.gov/pmc/article ... 6-0016.pdf
What's true is that there's always at least 40% UFA in fatty tissue, also PUFA, but mostly the MUFA Oleic Acid.
Coconut oil isn't all that great according to this paper:
https://gupea.ub.gu.se/bitstream/2077/3 ... 2909_1.pdf
It can be concluded that coconut fat as the main fat in the diet led to significantly higher TC
levels and LDL levels in adults compared to diets rich in HUFA, which is today
not considered to be beneficial when it comes to blood cholesterol in relation to health.
And now to the worst fact I learned. Palmitic Acid (which is abundant in dairy and coconut oil) is outright evil:
In contrast, when palmitic acid reaches the liver after absorption, it simply recirculates as palmitic acid in lipoproteins. Thus, dietary palmitic acid, along with lauric and myristic acids, elevates plasma cholesterol and LDL concentrations by down-regulating the hepatic receptor for LDL (5). (Connor, 1999)
The same author also writes how stearic acid, another SFA, lowers "the good" HDL levels.
Here is about which fats are being metabolized preferredly - and it's definitely not PUFA:
The oxidation of laurate was the highest of all fatty acids tested (Figure 4⇓). The next most highly oxidized fatty acid was linolenate (18:3n−3), followed by elaidate, linoleate, and oleate, which showed similar rates of oxidation. The oxidation of elaidate (trans 18:1n−9) appeared to be slightly higher than that of oleate (cis 18:1n−9) and the peak oxidation appeared to be delayed by ≈30 min (Figure 5⇓). The 2 long-chain saturated fatty acids were the least oxidized, with only 13% of stearate oxidized over the 9-h test. (DeLany, 2000)
Palmitic acid causes insulin resistance:
Palmitate-induced cellular insulin resistance was clarified by the reduced Akt phosphorylation, glucose uptake and Glut4 expression. Palmitate-caused myotube loss was clearly observed under microscope and proved by myotube counting and expression analysis of myotube marker genes. Moreover, palmitate-induced transcriptional suppression of three health benefit myokine genes (FNDC5, CTRP15 and FGF21) was found, and the different involvement of p38 and PI3K in the transcription of these genes was noticed. (Yang, 2013)
And causes diabetes even further by killing insulin making ß-cells of the pancreas (Maedler, 2001).
Oleic Acid seems to be the one king of FAs that is really only good (it can even reverse damage caused by palmitic acid):
Importantly, oleic acid, but not other long chain fatty acids such as palmitate, increased the expression of genes linked to fatty acid oxidation pathway in a SIRT1-PGC1α-dependent mechanism. As a result, oleic acid potently accelerated rates of complete fatty acid oxidation in skeletal muscle cells. These results illustrate how a single long chain fatty acid specifically controls lipid oxidation through a signaling/transcriptional pathway. Pharmacological manipulation of this lipid signaling pathway might provide therapeutic possibilities to treat metabolic diseases associated with lipid dysregulation. (Lim, 2013)
Further I was quite taken aback finding out that babies born to moms with untreated gestational diabetes (what Ray kind of describes as positive cause it supposedly makes the babies smarter) is also making them likely to develop diabetes later in life!
http://care.diabetesjournals.org/conten ... 6.abstract
So please be careful with Rays advice. And I'm curious if anyone can argue against this with positive studies. The ones mentioned surely can be attacked from certain angles, but there's a lot more that support these findings.
So all started because my blood lipid levels have gone bad from being spot on average before I started "peating". LDL is high now.
I was looking around once more and found quite shocking information. It is quite obvious and contradictory to things Ray said. I did my body wrong with all the coconut oil and butter rather than olive oil and fish. There's an effect just like Ray describes that harms the body through fatty acid composition for a long time, but it's not about PUFA but the most common SFA in dairy, palmitic acid - which is evil (see at the end).
A great summary and mountain of information can be found on
http://edubily.de/2014/10/fette-das-der ... n-teil-iv/
but it is in German.
I thought Ray said that babies are all created saturated - which of course would SFA seem quite optimal.
http://www.ncbi.nlm.nih.gov/pmc/article ... 6-0016.pdf
What's true is that there's always at least 40% UFA in fatty tissue, also PUFA, but mostly the MUFA Oleic Acid.
Coconut oil isn't all that great according to this paper:
https://gupea.ub.gu.se/bitstream/2077/3 ... 2909_1.pdf
It can be concluded that coconut fat as the main fat in the diet led to significantly higher TC
levels and LDL levels in adults compared to diets rich in HUFA, which is today
not considered to be beneficial when it comes to blood cholesterol in relation to health.
And now to the worst fact I learned. Palmitic Acid (which is abundant in dairy and coconut oil) is outright evil:
In contrast, when palmitic acid reaches the liver after absorption, it simply recirculates as palmitic acid in lipoproteins. Thus, dietary palmitic acid, along with lauric and myristic acids, elevates plasma cholesterol and LDL concentrations by down-regulating the hepatic receptor for LDL (5). (Connor, 1999)
The same author also writes how stearic acid, another SFA, lowers "the good" HDL levels.
Here is about which fats are being metabolized preferredly - and it's definitely not PUFA:
The oxidation of laurate was the highest of all fatty acids tested (Figure 4⇓). The next most highly oxidized fatty acid was linolenate (18:3n−3), followed by elaidate, linoleate, and oleate, which showed similar rates of oxidation. The oxidation of elaidate (trans 18:1n−9) appeared to be slightly higher than that of oleate (cis 18:1n−9) and the peak oxidation appeared to be delayed by ≈30 min (Figure 5⇓). The 2 long-chain saturated fatty acids were the least oxidized, with only 13% of stearate oxidized over the 9-h test. (DeLany, 2000)
Palmitic acid causes insulin resistance:
Palmitate-induced cellular insulin resistance was clarified by the reduced Akt phosphorylation, glucose uptake and Glut4 expression. Palmitate-caused myotube loss was clearly observed under microscope and proved by myotube counting and expression analysis of myotube marker genes. Moreover, palmitate-induced transcriptional suppression of three health benefit myokine genes (FNDC5, CTRP15 and FGF21) was found, and the different involvement of p38 and PI3K in the transcription of these genes was noticed. (Yang, 2013)
And causes diabetes even further by killing insulin making ß-cells of the pancreas (Maedler, 2001).
Oleic Acid seems to be the one king of FAs that is really only good (it can even reverse damage caused by palmitic acid):
Importantly, oleic acid, but not other long chain fatty acids such as palmitate, increased the expression of genes linked to fatty acid oxidation pathway in a SIRT1-PGC1α-dependent mechanism. As a result, oleic acid potently accelerated rates of complete fatty acid oxidation in skeletal muscle cells. These results illustrate how a single long chain fatty acid specifically controls lipid oxidation through a signaling/transcriptional pathway. Pharmacological manipulation of this lipid signaling pathway might provide therapeutic possibilities to treat metabolic diseases associated with lipid dysregulation. (Lim, 2013)
Further I was quite taken aback finding out that babies born to moms with untreated gestational diabetes (what Ray kind of describes as positive cause it supposedly makes the babies smarter) is also making them likely to develop diabetes later in life!
http://care.diabetesjournals.org/conten ... 6.abstract
So please be careful with Rays advice. And I'm curious if anyone can argue against this with positive studies. The ones mentioned surely can be attacked from certain angles, but there's a lot more that support these findings.