J
j.
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I found some people on the internet claiming they had neuropathy symptoms from the P5P form of vitamin B6, the one that's supposed to be safer. One used a coated tablet, other sublingual. Maybe some additives caused the problem, not the P5P. One claimed later B12 supplementation cured the problems.
These are anecdotes, rumors, but caught my attention and here they are:
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7 months later...
These are anecdotes, rumors, but caught my attention and here they are:
I developed B6 toxicity while using the co-enzymated form of B6 (P5P). Thus far I've not seen anything on the internet that suggests this can occur-which is why I wanted especially to post this.
For me, I began to experience neuropathy symptoms 2 days after starting the P5P. I was using the enteric coated tablet form of P5P, and taking 33mg Coenzymated Vitamin B-6 (from 50mg P5P), twice a day.
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So, all my research on P5P indicates that it is supposedly without the risks of regular B6. However, I have just experienced the unfortunate effects of B6 toxictiy after just a few days on P5P. I have so far found 4 or 5 others who have had similar experiences.
I took 50mg of P5P in sublingual form on day 1 and I experienced notable anxiety and irritation for about 4 hours afterwards. On day 2 I broke up the dose into two 25mg doses and noticed some mild anxiety after each dose. Day 3 I did the same and noticed a mild tingling in my left foot. Day 4 I dosed the same and noticed profound burning and tingling in both foot and my left hand. I stopped immediately.
It's been about a week and the symptoms have intensified.
7 months later...
Read more.I wanted to post a resolution to this as I finally recovered.
I took MASSIVE amounts of methylcobalamin and the neuropathy resolved literally in hours...then returned slowly over the next day (perhaps when the B12 was fully utilized). I repeated this process a few times and the neuropathy is completely gone.