David PS
Member
Thanks, I know 2 people who have had bariatric surgery and they now have bone loss. They look frail. Bariatric surgery is basically a surgically-enforced fast and bone loss is a known side effect. I thought it was the result of reduced intestinal absorption of calcium. Lack of sufficient body fat appears to be an additional factor to add to the flow chart in this article.Weight-loss semaglutides that mimic calorie restriction like Ozempic appears to drive bone loss:
"An unintended consequence of caloric restriction may be bone loss. Cutting calories can drive fat loss in subcutaneous body fat depots. Yay. Great right? Except an emerging line of research is consistently showing that caloric restriction most likely drives a shift in bone marrow stem cells that result in BONE LOSS.
Postoperative Osteoporosis in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy
Obesity has become a worldwide epidemic accompanied by adverse health effects. The limited efficiency of traditional weight reduction regimens has led to a substantial increase in the use of bariatric surgery. Today, sleeve gastrectomy (SG) and Roux-en-Y-gastric bypass (RYGB) are the most used...
www.mdpi.com
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