lindsay
Member
I think the idea might be that if there is a lot of inflammation and therefore a reduced lumen diameter, and if there is low energy available (eg low metabolism or low CO2), then it takes a lot of serotonin to stimulate enough peristalsis to keep the GI moving adequately.
If the inflammation can be reduced, then it's not so hard to push things through.
And if the metabolism is strong, maybe the gut keeps moving better anyway, even with less serotonin? I'm not sure about this last one.
I don't think the serotonin is all in the lumen of the gut, and so excreted (maybe some of it is, I don't know). I think it is in the tissue of the gut - acting on the muscles etc somehow to kick them into action - so more systemic.
Yes - this makes sense. I am just trying to make sense of what is actually causing serotonin issues and what is normal and healthy. Some foods definitely trigger serotonin - but for me, I only feel terrible and "serotonin" like when I cannot have a comfortable (or any) bowel movement. And this is what I don't understand about anti-serotonin drugs because I would imagine they would lower bowel movement frequency.