Kelj
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Keto diet: Scientists find link to diabetes risk
Keto diet: Scientists find link to diabetes risk
This article makes claims about the healthfulness of a ketogenic diet and explains "diabetes" in ways I have come to doubt. However, they are on the right track when they recognize the link between oxidizing fat and the rise of blood glucose.
Following, are some reasons why I think the way almost everyone thinks about blood glucose is wrong:
1.
symptoms of hypoglycemia. You'll learn to spot yours.
Early symptoms include:
Without treatment, you might get more severe symptoms, including:
Does LOW blood glucose sound like something our brain would try to protect us from? So....
2. Brain may play key role in blood sugar metabolism and diabetes development
This article admits the brain decides the blood sugar level, but peculiarly calls the interaction between brain and pancreas "the failure of both systems", rather than a rational decision on the part of the brain, which is what I think it is. I am not alone....
3. Not So Fast With the Insulin? - Diabetes Self-Management
"Now a recent report by Roger Unger, MD, of the UT Southwestern Medical Center, says giving insulin is one of the worst things you can do for overweight people with Type 2......Giving more insulin to an insulin-resistant patient is akin to raising the blood pressure of a patient with high blood pressure to overcome resistance to blood flow. Instead, you would try to reduce the resistance,” Dr. Unger said.....The beta cells may “turn off” as a defense against fat. Without insulin, fat cells can’t take in more outside fat, and they will actually release fat to be used as energy. So injecting insulin might go against what the body is trying to do for itself."
Ray explains a process called Neuro glucopenia or Neuroglycopenia.
Neuroglycopenia - Wikipedia
"Neuroglycopenia is a shortage of glucose(glycopenia) in the brain, usually due to hypoglycemia. Glycopenia affects the function of neurons, and alters brain function and behavior.....A few types of specialized neurons, especially in the hypothalamus, act as glucose sensors, responding to changing levels of glucose by increasing or decreasing their firing rates. They can elicit a variety of hormonal, autonomic, and behavioral responses to neuroglycopenia. The hormonal and autonomic responses include release of counterregulatory hormones. There is some evidence that the autonomic nervous system can alter liver glucose metabolismindependently of the counterregulatory hormones."
The brain senses a need for MORE glucose and the regulatory systems make adjustments to increase the blood glucose. As Dr. Unger said, trying to lower the blood sugar is going "against what the body is trying to do."
4. The brain is trying to protect us from coma and death. The high blood sugar enables the brain and the most vital organs to keep functioning.
What prompts the brain to raise the blood glucose?
Many stresses can temporarily or for longer periods cause the brain to raise the blood glucose level. As Ray says, stress seems to be seen by the body as the need for more sugar.
When the diet is not providing enough glucose, as in a low carb or ketogenic diet, this is seen by the brain as a stress, as a need for more glucose. I believe the genesis of a state of constant high blood glucose is the start of a low carb diet or even a low calorie diet.
As the Eating Disorder Institute states:
Diabetes Mellitus Type 2, Metformin, Disease Risk and You
"diabetes mellitus type 2 is not a disease— it’s a risk factor for developing disease. That means that not everyone with diabetes type 2 (treated or untreated) will ever develop any disease state that is more strongly correlated with the presence of type 2 than for those who don’t have the condition."
The reason chronic high blood sugar is seen as a risk factor in developing disease is because it is so often seen in conjunction with heart disease, retinopathy, kidney failure and poor peripheral circulation. The reason why few are getting to the root of explaining the effects of high blood glucose is they insist on seeing the whole issue backwards. High blood glucose is not the cause of the conditions it appears with. Excess weight, high blood glucose, retinopathy, kidney disease, heart disease and peripheral circulation troubles are all the results of carb starvation and low calorie diets in general. The body is degenerating and if the brain didn't adjust metabolism rate down and blood glucose up, we would break down faster and die.
5. The therapies create the so-called complications of "diabetes:
Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF. - PubMed - NCBI
This article explains the connection between insulin therapy and neuropathy.
Insulin inhibits dog vascular smooth muscle contraction and lowers Ca2+i by inhibiting Ca2+ influx. - PubMed - NCBI
This one talks about how smooth muscle is effected by insulin.
Also,
Insulin effect on body: Side effects, myths, and tips
"researchers found that the insulin therapy group had an increased risk of a range of complications, including:
Low calorie and especially low carbohydrate or ketogenic diets or any other starvation like intermittent fasting is what prompts the brain to raise the blood glucose. The only rational way to encourage the brain to maintain a lower glucose is to provide plenty of carbohydrate in the diet. High-carbohydrate diets and insulin-dependent diabetics.
Keto diet: Scientists find link to diabetes risk
This article makes claims about the healthfulness of a ketogenic diet and explains "diabetes" in ways I have come to doubt. However, they are on the right track when they recognize the link between oxidizing fat and the rise of blood glucose.
Following, are some reasons why I think the way almost everyone thinks about blood glucose is wrong:
1.
symptoms of hypoglycemia. You'll learn to spot yours.
Early symptoms include:
- Confusion
- Dizziness
- Feeling shaky
- Hunger
- Headaches
- Irritability
- Pounding heart; racing pulse
- Pale skin
- Sweating
- Trembling
- Weakness
- Anxiety
Without treatment, you might get more severe symptoms, including:
- Poor coordination
- Poor concentration
- Numbness in mouth and tongue
- Passing out
- Seizures
- Nightmares or bad dreams
- Coma
Does LOW blood glucose sound like something our brain would try to protect us from? So....
2. Brain may play key role in blood sugar metabolism and diabetes development
This article admits the brain decides the blood sugar level, but peculiarly calls the interaction between brain and pancreas "the failure of both systems", rather than a rational decision on the part of the brain, which is what I think it is. I am not alone....
3. Not So Fast With the Insulin? - Diabetes Self-Management
"Now a recent report by Roger Unger, MD, of the UT Southwestern Medical Center, says giving insulin is one of the worst things you can do for overweight people with Type 2......Giving more insulin to an insulin-resistant patient is akin to raising the blood pressure of a patient with high blood pressure to overcome resistance to blood flow. Instead, you would try to reduce the resistance,” Dr. Unger said.....The beta cells may “turn off” as a defense against fat. Without insulin, fat cells can’t take in more outside fat, and they will actually release fat to be used as energy. So injecting insulin might go against what the body is trying to do for itself."
Ray explains a process called Neuro glucopenia or Neuroglycopenia.
Neuroglycopenia - Wikipedia
"Neuroglycopenia is a shortage of glucose(glycopenia) in the brain, usually due to hypoglycemia. Glycopenia affects the function of neurons, and alters brain function and behavior.....A few types of specialized neurons, especially in the hypothalamus, act as glucose sensors, responding to changing levels of glucose by increasing or decreasing their firing rates. They can elicit a variety of hormonal, autonomic, and behavioral responses to neuroglycopenia. The hormonal and autonomic responses include release of counterregulatory hormones. There is some evidence that the autonomic nervous system can alter liver glucose metabolismindependently of the counterregulatory hormones."
The brain senses a need for MORE glucose and the regulatory systems make adjustments to increase the blood glucose. As Dr. Unger said, trying to lower the blood sugar is going "against what the body is trying to do."
4. The brain is trying to protect us from coma and death. The high blood sugar enables the brain and the most vital organs to keep functioning.
What prompts the brain to raise the blood glucose?
Many stresses can temporarily or for longer periods cause the brain to raise the blood glucose level. As Ray says, stress seems to be seen by the body as the need for more sugar.
When the diet is not providing enough glucose, as in a low carb or ketogenic diet, this is seen by the brain as a stress, as a need for more glucose. I believe the genesis of a state of constant high blood glucose is the start of a low carb diet or even a low calorie diet.
As the Eating Disorder Institute states:
Diabetes Mellitus Type 2, Metformin, Disease Risk and You
"diabetes mellitus type 2 is not a disease— it’s a risk factor for developing disease. That means that not everyone with diabetes type 2 (treated or untreated) will ever develop any disease state that is more strongly correlated with the presence of type 2 than for those who don’t have the condition."
The reason chronic high blood sugar is seen as a risk factor in developing disease is because it is so often seen in conjunction with heart disease, retinopathy, kidney failure and poor peripheral circulation. The reason why few are getting to the root of explaining the effects of high blood glucose is they insist on seeing the whole issue backwards. High blood glucose is not the cause of the conditions it appears with. Excess weight, high blood glucose, retinopathy, kidney disease, heart disease and peripheral circulation troubles are all the results of carb starvation and low calorie diets in general. The body is degenerating and if the brain didn't adjust metabolism rate down and blood glucose up, we would break down faster and die.
5. The therapies create the so-called complications of "diabetes:
Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF. - PubMed - NCBI
This article explains the connection between insulin therapy and neuropathy.
Insulin inhibits dog vascular smooth muscle contraction and lowers Ca2+i by inhibiting Ca2+ influx. - PubMed - NCBI
This one talks about how smooth muscle is effected by insulin.
Also,
Insulin effect on body: Side effects, myths, and tips
"researchers found that the insulin therapy group had an increased risk of a range of complications, including:
- heart attack
- stroke
- eye complications
- kidney problems
- the need to increase the dose and complexity of the treatment plan over time
- the increased risk of severe hypoglycemia
- a potentially higher risk of death
- a possible increased risk of specific cancers"
Low calorie and especially low carbohydrate or ketogenic diets or any other starvation like intermittent fasting is what prompts the brain to raise the blood glucose. The only rational way to encourage the brain to maintain a lower glucose is to provide plenty of carbohydrate in the diet. High-carbohydrate diets and insulin-dependent diabetics.