LucyL
Member
- Joined
- Oct 21, 2013
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Since Dr. Peat has written on clotting disorders, I have wondered for a while about his take on hemorrhagic fevers. While Ebola is the most well known, there is actually a long list of illnesses that can be hemorrhagic, including Dengue, hantavirus (also known in America as "four corners disease"), yellow fever, bird flu (H7N9 etc), Chikungunya, H1N1 (swine flu) can produce hemorrhagic pneumonia as well.
So I finally asked what he would see as an appropriate therapeutic approach to the hemorrhaging associated with these illnesses, and this was his response:
I think some of that answer comes from studies like these: Analysis of Human Peripheral Blood Samples from Fatal and Nonfatal Cases of Ebola (Sudan) Hemorrhagic Fever and Inflammatory responses in Ebola virus-infected patients.
So what practical applications could be deduced from this?
Usually the word "oxidative" is followed by "damage", and things like iron and fish oil come to mind.
There is some evidence that D3 will increase plasma interferon levels Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
Emodin can block nitric oxide formation. Thyroid and progesterone of course are antiinflammatory and block nitric oxide. One thinks of aspirin too, and Vit K.
Reports seem to indicate that current supportive treatment (experimental drugs aside) simply includes maintaining blood pressure, fluids and antibiotics for secondary infections. If more is being done, nobody seems to be talking about it.
So I finally asked what he would see as an appropriate therapeutic approach to the hemorrhaging associated with these illnesses, and this was his response:
Ebola infection seems to involve a lack of interferon, and the amount of nitric oxide in the blood increases in proportion to the intensity of the symptoms. Reductive stress/inflammation that activates interleukin-1 and arachidonic acid metabolites can inhibit interferon, and at the same time increase the production of nitric oxide. Resistance would be improved by oxidative and antiinflammatory things.
I think some of that answer comes from studies like these: Analysis of Human Peripheral Blood Samples from Fatal and Nonfatal Cases of Ebola (Sudan) Hemorrhagic Fever and Inflammatory responses in Ebola virus-infected patients.
So what practical applications could be deduced from this?
Usually the word "oxidative" is followed by "damage", and things like iron and fish oil come to mind.
There is some evidence that D3 will increase plasma interferon levels Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
Emodin can block nitric oxide formation. Thyroid and progesterone of course are antiinflammatory and block nitric oxide. One thinks of aspirin too, and Vit K.
Reports seem to indicate that current supportive treatment (experimental drugs aside) simply includes maintaining blood pressure, fluids and antibiotics for secondary infections. If more is being done, nobody seems to be talking about it.