tankasnowgod
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- Jan 25, 2014
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I've been getting more interested in the Calcium:Phosphate ratio recently. Peat suggested in a few interviews that phosphates are often used to fatten up livestock, and to add extra water weight to meat. Excess phosphate should have the same effects in humans. Doing some searching around, it seems that supplemental calcium (in the form of Calcium Carbonate) has a few studies to show that it can act as a phosphate binder, and lower high levels of serum phosphate-
That got me wondering if Calcium, itself, has a diuretic effect. Apparently, it does, and this was well known in the 1920s-
The salts they used were calcium lactate, and calcium cholrid[e], which contained 13% and 27% calcium respectively. They used 18g of calcium lactate, and from 9-18g of calcium chlorid[e]. This means the patients were getting between 2.34 and 4.86 grams of supplemental calcium a day. Some of the patients lost massive amounts of water weight. One patient looks to have dropped over 55 pounds in less than 20 days. No other diuretics were used, but a low salt and fluid restricted diet was usually used (although at least one patient had success without restricting either).
They seem to think it's mostly due to the calcium itself, so calcium carbonate, eggshell, and oystershell would probably work, in similar calcium doses. Calcium carbonate is 40% calcium, which would suggest 6-12 grams of calcium carbonate a day.
This now gives us three "Peaty" diuretics...... Acetazolamide, Urea (in doses of 30-120g a day), and calcium (in doses from about 2-5g).
Chronic Calcium Carbonate Therapy in Uremia
Twenty-one azotemic patients received 3.36 to 6.72 gm (67 to 134 mEq) of calcium carbonate for treatment of acidosis or hypocalcemia or both. All patients were studied for at least two weeks, and 15 studies were continued for 3 to 12 months. A mean increase in serum calcium of 1.6 mg/100 ml and...
jamanetwork.com
That got me wondering if Calcium, itself, has a diuretic effect. Apparently, it does, and this was well known in the 1920s-
CALCIUM TREATMENT FOR EDEMA
Meyer and Cohn,1 in 1911, studied the effect of various salts on the weight and mineral balance in normal infants. They found that by giving calcium salts they could cause a decrease in weight due to water loss. In the case of calcium chlorid, they found that the calcium ion seemed to be largely...
jamanetwork.com
We have tried the effect of large doses of calcium salts (from 12 to18 gm. daily) in cases of massive edema of diabetic and nephritic origin. In six of seven cases, most of which had been resistant to other methods of treatment, edema disappeared completely. In one case, edema disappeared, but the part played by the calcium is questionable. In two cases of nephritis, edema recurred later. None of these cases were complicated by significant myocardial damage, and in none was any other diuretic given with the calcium.
In the few instances in which we used small doses of calcium (from 1 to 3 gm. daily), little or no effect was observed. In some of the cases, edema was reduced by calcium lactate. In other cases, calcium chlorid seemed more effective. Large doses of calcium do not seem to increase the amount of serum calcium. In one case of chronic glomerular nephritis, renal function was definitely improved as the edema subsided.
In one case of diabetic edema, the basal metabolic rate rose during the administration of calcium from — 13, April 21, to an average of -j- 57, May 9. A similar dose of calcium did not produce a change in the basal metabolic rate of a normal person. In the other cases of edema discussed, the administration of calcium had no effect on the basal metabolic rate. The high
calcium content of milk may explain its diuretic action, and thus its popularity in the treatment of acute nephritis.
The salts they used were calcium lactate, and calcium cholrid[e], which contained 13% and 27% calcium respectively. They used 18g of calcium lactate, and from 9-18g of calcium chlorid[e]. This means the patients were getting between 2.34 and 4.86 grams of supplemental calcium a day. Some of the patients lost massive amounts of water weight. One patient looks to have dropped over 55 pounds in less than 20 days. No other diuretics were used, but a low salt and fluid restricted diet was usually used (although at least one patient had success without restricting either).
They seem to think it's mostly due to the calcium itself, so calcium carbonate, eggshell, and oystershell would probably work, in similar calcium doses. Calcium carbonate is 40% calcium, which would suggest 6-12 grams of calcium carbonate a day.
This now gives us three "Peaty" diuretics...... Acetazolamide, Urea (in doses of 30-120g a day), and calcium (in doses from about 2-5g).