It’s been mentioned here before that calcium can function as a bile binder but I thought I’d post this study as confirmation of the magnitude of the effect.
“high-dose fiber supplementation caused a reduction in fecal concentrations of total bile acids (52% reduction; P = .001) and deoxycholic acid (48% reduction; P = .003). High-dose calcium supplementation also had a significant, but lower, effect at 9 months versus 0 months on the geometric mean total bile acid (35% reduction; P = .044) and deoxycholic fecal bile acid (36% reduction; P = .052) concentrations.”
While wheat bran was slightly more effective, calcium carbonate has other benefits that definitely make it a better choice. The dose was 1500 mg of elemental calcium in the form of calcium carbonate(~3750mg).
Randomized, double-blinded, placebo-controlled study of effect of wheat bran fiber and calcium on fecal bile acids in patients with resected adenomatous colon polyps - PubMed
Phase III studies of these agents in the prevention of adenoma recurrence are necessary to confirm this hypothesis and have now been initiated at multiple institutions.
pubmed.ncbi.nlm.nih.gov
“high-dose fiber supplementation caused a reduction in fecal concentrations of total bile acids (52% reduction; P = .001) and deoxycholic acid (48% reduction; P = .003). High-dose calcium supplementation also had a significant, but lower, effect at 9 months versus 0 months on the geometric mean total bile acid (35% reduction; P = .044) and deoxycholic fecal bile acid (36% reduction; P = .052) concentrations.”
While wheat bran was slightly more effective, calcium carbonate has other benefits that definitely make it a better choice. The dose was 1500 mg of elemental calcium in the form of calcium carbonate(~3750mg).