Apple
Member
- Joined
- Apr 15, 2015
- Messages
- 1,297
Malnutrition can cause thiamine deficiency. Thiamine deficiency has been associated with lactic acidosis. People suffering from SBS, abnormal gut flora and/or malabsorption syndromes are at increased risk for thiamine deficiency. This deficiency, when paired with the elevated lactate production from abnormal gut flora, may lead to large amounts of excess lactate that cannot be effectively metabolized.What exactly is "the main issue" you speak of? Is this a semantics thing? Are we speaking of two entirely different things? I'm referring to mitochondrial oxidative metabolism going awry without thiamine that is needed as a co-enzyme in the process for several steps. Without thiamine, oxidative metabolism gets derailed which causes lactic acid to be made as the end product instead of ATP+carbon dioxide. I'm talking about systemic lactic acidosis. I'm not talking about the thiamine that gets made in the gut by some bacteria that hopefully reside there.
I'm just wondering why you haven't fixed your thiamine deficiency so far?