When is best time to use a binder of sorts? Bile is released during a meal, so is it ideal to use it right after eating? Or how about 30 minutes to 2 hours after eating? Or what if a supplement is used to help increase bile, such as artichoke, should a binder be used right after supplementing? I have major endotoxin issues and my liver/kidneys are really taking a hit and would like to relieve the burden on them. Symptoms get worse when I try to eradicate or treat infections in my body, ie Lyme, Candida.