Well, progesterone and acetylcholine act in opposite directions. In fact, progesterone induces acetylcholinesterase in order to degrade ACh ASAP, and Peat considers this one of the most important nerve protecting, intelligence enhancing actions of progesterone. Acetylcholine destroys the brain/nervous system if it accumulates beyond what's needed. Acetylcholine is the main neurotransmitter of the inflammatory branch of the autonomic nervous system: the parasympathetic nervous system. If you'd like more info Autonomic systemsThe current fibroid swelling is an odd thing. For a few weeks I've been taking an herbal acetylcholinesterase (AChE, sorry if you already knew that) inhibitor
Maybe the positive effects from the herb are due to effects on something else? Anyways, I thought you might be interested in this info :)