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- Oct 30, 2015
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Aromatase activity induction in human adipose fibroblasts by retinoic acids via retinoic acid receptor α - PubMed
Estrogen synthesis in adipose tissue is associated with the development of breast cancer. Tumors are preferentially found in breast quadrants with strongest expression of the cytochrome P450 aromatase (encoded by the gene CYP19A1). Several promoters regulated by various hormonal factors drive...
pubmed.ncbi.nlm.nih.gov
The looked at the effect of vit A on aromatase in breast tissue fibroblasts.
I'd like to know if anyone has reasonable objections based on study design, methodology etc.