wavelength123
Member
- Joined
- May 15, 2020
- Messages
- 135
Disclaimer - y’all may or may not relate but I live in a huge metropolitan area and stressing less / leaving the city for a nice and quiet lifestyle far away from ambulance sirens, peak hour subways, and pollution is not an option.
So I’ve read a number of interesting biochem type studies where LH is shown to increase all types of enzymes involved in steroidogenesis. We know HCG tends to increase aromatase, I think 5a reductase also goes up, and I was nerding on 11b-HSD’s which LH also increase. It seems to me that all enzymes and thusly all hormones increase across the board. 11bHSD1 in particular increases cortisol.
My personal experience with HCG showed great T (total and free) and E2 improvements... but cortisol was borderline high.
Therefore I’m here guessing that if one has a high ish Cortisol / Test ratio naturally, be it because of personal stress or just a generally shitty fight or flight environment, HCG won’t cut it. Like what’s the benefit going from 400 ng/dL up to 700+ (with free T and E2 doubling up as well) if cortisol is nearly beyond normal range. Same goes for SERMS by the way, which also indiscriminately bump it all up. I know cortisol is extremely useful for normal human physiology but if it goes high there’s a reason for it and that is big bad stress. So I guess the point of my thread is to make sure that you guys on HCG monitor as many hormones as possible not just T/E2, and especially cortisol.
I’ve been fooling around with HCG only and then HCG+Trestolone but realistically I think that TRT is the only way we’ve got to totally turn around a bad T/C ratio.
I can share studies in here if this gets some traction. For now I’m only sharing skepticism about HCG
So I’ve read a number of interesting biochem type studies where LH is shown to increase all types of enzymes involved in steroidogenesis. We know HCG tends to increase aromatase, I think 5a reductase also goes up, and I was nerding on 11b-HSD’s which LH also increase. It seems to me that all enzymes and thusly all hormones increase across the board. 11bHSD1 in particular increases cortisol.
My personal experience with HCG showed great T (total and free) and E2 improvements... but cortisol was borderline high.
Therefore I’m here guessing that if one has a high ish Cortisol / Test ratio naturally, be it because of personal stress or just a generally shitty fight or flight environment, HCG won’t cut it. Like what’s the benefit going from 400 ng/dL up to 700+ (with free T and E2 doubling up as well) if cortisol is nearly beyond normal range. Same goes for SERMS by the way, which also indiscriminately bump it all up. I know cortisol is extremely useful for normal human physiology but if it goes high there’s a reason for it and that is big bad stress. So I guess the point of my thread is to make sure that you guys on HCG monitor as many hormones as possible not just T/E2, and especially cortisol.
I’ve been fooling around with HCG only and then HCG+Trestolone but realistically I think that TRT is the only way we’ve got to totally turn around a bad T/C ratio.
I can share studies in here if this gets some traction. For now I’m only sharing skepticism about HCG