Vaping may lower men's sperm counts and shrink their testicles, study suggests

[ALS]

Vaping may lower sperm counts, sap libido, and shrink the testicles, scientists warn.

In research on male rats, experts from Turkey tested what effect exposure to smoke from e-cigarettes and normal cigarettes had on the rodents' sexual health.

They measured how much sperm the animals could make, what their testicles looked like under a microscope and markers of stress in the blood and genitals.

The authors wrote: ‘It should be considered that although [e-cigarette] liquid has been introduced as harmless in smoking cessation studies, it could increase oxidative stress and cause morphological changes in the testicle.’ Vaping 'shrinks the testicles and causes sperm counts to plummet'

 

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Vaping may lower sperm counts, sap libido, and shrink the testicles, scientists warn.

In research on male rats, experts from Turkey tested what effect exposure to smoke from e-cigarettes and normal cigarettes had on the rodents' sexual health.

They measured how much sperm the animals could make, what their testicles looked like under a microscope and markers of stress in the blood and genitals.

The authors wrote: ‘It should be considered that although [e-cigarette] liquid has been introduced as harmless in smoking cessation studies, it could increase oxidative stress and cause morphological changes in the testicle.’ Vaping 'shrinks the testicles and causes sperm counts to plummet.

“It is important to evaluate the health effects of e-cigarettes when e-liquid is heated and aerosolized; under such conditions, chemical reactions may result in the formation of new compounds. For example, although refill liquids can contain carbonyl compounds such as reactive aldehydes, heating can enhance the concentrations of these compounds in the aerosol.

Several studies have shown that e-cigarettes emit toxic carbonyl compounds, generated from thermal decomposition of e-liquid ingredients. Carbonyl compounds such as formaldehyde, acetaldehyde, acrolein, and glyoxal, which have been found in e-cigarette aerosols, are potentially hazardous and may induce various health effects in users. Formaldehyde is classified as a human carcinogen (Group 1) by the International Agency for Research on Cancer (IARC), and acetaldehyde is classified as possibly carcinogenic to humans (Group 2B) (Bekki et al., 2014). Glycidol is a probable carcinogen and acrolein causes irritation of the nasal cavity and damages the lining of the lungs (ATSDR, 2007; NTP, 2007). How formaldehyde-releasing agents (hemiacetals) behave in the respiratory tract is currently unknown. Glyoxal and methylglyoxal show mutagenicity. The amount of carbonyl compounds in e-cigarettes varied significantly not only among different brands but also among different samples of the same products. Although, in most cases, detected levels of carbonyl compounds were lower than those in combustible tobacco cigarette smoke, very high levels of formaldehyde were also reported in e-cigarette aerosols (a comparison of toxicants from combustible tobacco cigarette smoke and e-cigarette aerosols is discussed in Chapter 18) (Canistro et al., 2017; Gillman et al., 2016).

Uchiyama and colleagues (2010, 2013) measured carbonyl compounds in e-cigarette aerosols using high-performance liquid chromatography (see also Bekki et al., 2014; Ohta et al., 2011). The authors tested 13 brands of Japanese e-cigarettes and detected several derivative peaks of carbonyl compounds, including formaldehyde, acetaldehyde, acetone, acrolein, propanal, crotonaldehyde, butanal, glyoxal, and methylglyoxal (Bekki et al., 2014; Ohta et al., 2011; Uchiyama et al., 2013). Four out of the 13 e-cigarette brands did not generate any carbonyl compounds. The other nine e-cigarette brands generated various carbonyl compounds. The maximum concentrations of formaldehyde, acetaldehyde, acrolein, propanal, glyoxal, and methylglyoxal were 140, 120, 40, 46, 23, and 21 µg/10 puffs, respectively.

Goniewicz and colleagues (2014) measured 15 carbonyl compounds in aerosol generated from 12 e-cigarette brands. Only four carbonyl compounds (formaldehyde, acetaldehyde, acrolein, and o-methylbenzaldehyde) were found in aerosols and these compounds were identified in nearly all examined e-cigarettes. The content of formaldehyde ranged from 2.0 mg to 56.1 mg, acetaldehyde from 1.1 mg to 13.6 mg, and acrolein from 0.7 mg to 41.9 mg per e-cigarette (150 puffs).

Kosmider and colleagues (2014) tested 13 samples of aerosol generated from Polish e-cigarettes and detected formaldehyde and acetaldehyde in 8 of them. The amounts of formaldehyde and acetaldehyde in e-cigarette aerosols at a lower voltage were on average 13- and 807-fold lower than those in combustible tobacco cigarette smoke, respectively. E-cigarette aerosols generated from PG-based e-liquids were found to have the highest levels of carbonyls. Furthermore, different e-cigarettes showed large variations in carbonyl levels.

Hutzler and colleagues (2014) measured formaldehyde in e-cigarette aerosol and estimated that exposure to formaldehyde can be comparable with combustible tobacco cigarettes. They measured 20 to 50 µg of formaldehyde per 10 puffs in the final fractions, which roughly corresponds to the expected exposure from smoking one combustible tobacco cigarette.

Flora and colleagues (2016) tested the aerosols of four MarkTen® e-cigarettes (rechargeable with disposable cartridges) for potential degradation products. They found formaldehyde levels that varied from 0.09 to 0.33 µg/puff. The same research team found formaldehyde residues in both the gas (approximately 30 percent) and liquid (approximately 70 percent) phases of an aerosol (Flora et al., 2017).

Blair and colleagues (2015) measured acrolein in aerosol from e-cigarettes and tobacco smoke and found that five puffs of an e-cigarette emitted 0.290 ± 0.018 µg of acrolein while nine puffs on a combustible tobacco cigarette emitted 2.61 ± 0.16 µg of this toxicant. There was a substantial range in the relative standard deviations reported for all mean value measurements, suggesting inconsistencies across products in the release of these chemicals.

Papousek and colleagues (2014) measured acrylamide and acrolein in tobacco smoke and three e-cigarette aerosol samples. The e-cigarette aerosol samples contained no detectable levels of acrylamide. Acrolein levels in combustible tobacco cigarette smoke varied from 4.48 to 8.27 µg per cigarette while levels detected in an equivalent sample of e-cigarette aerosol varied from 0.17 to 3.70 µg.

Sleiman and colleagues (2016) detected up to 31 compounds, including formaldehyde, acetaldehyde, glycidol, acrolein, acetol, and diacetyl, in e-cigarette aerosols from different devices. Emission rates were significantly higher for a single-coil versus a double-coil device, ranging from tens to thousands of nanograms of toxicants per milligram of e-liquid aerosol.

Tayyarah and Long (2014) tested 55 harmful and potentially harmful constituents in e-cigarette aerosol (blu and SKYCIG brands) and quantified three carbonyls (acrolein, acetaldehyde, and propionaldehyde) at levels 86 to 544 times lower than combustible tobacco cigarette smoke.

Table 5-5 summarizes experimental studies to determine carbonyl compounds in e-cigarette aerosols, their setups (i.e., methods to trap and analyze carbonyls, e-liquids used), and results. Because carbonyl compounds were primarily detected in aerosol and only traces have been reported in e-liquids, it has been suggested that these compounds are generated when e-liquid ingredients are heated. Figure 5-1 illustrates the pathways and by-products formed during thermal dehydration of PG and glycerol as postulated by Sleiman and colleagues (2016). Hutzler and colleagues (2014) incubated e-cigarette liquids at various temperatures and found levels of acetaldehyde and formaldehyde from 10-fold to 20-fold higher at the temperature of 150°C compared with ambient temperatures for samples containing PG. They did not observe this effect at 100°C.”

Toxicology of E-Cigarette Constituents - Public Health Consequences of E-Cigarettes - NCBI Bookshelf

 

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Vaping isn’t looking too sexy….

“Sexual health risks associated with vaping include the following:

• Erectile dysfunction
• Decreased testosterone levels
• Delayed sexual arousal
• Low libido
• Psychological problems”

“Firstly, vaping and e-Cigarette use can hinder the sufficient flow of blood to the penis.

A healthy stream of blood flow is a necessary component in sustaining an erection in men. Blockages or problems with this functioning can lead men experiencing erectile dysfunction.”

Can Vaping Cause Erectile Dysfunction in Men? - Priority Men's Medical

Does vaping lead to erectile dysfunction? Yes, vaping can lead to erectile dysfunction and a host of other sexual dysfunction conditions. Learn more about it.

prioritymensmedical.com

 

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“The most common liquid carrier sounds innocent and natural enough: “vegetable glycerin.” Maybe it’s fine to eat in your food (and is labelled as “Generally Recognized As Safe” for oral consumption), but when you are combusting it in a vape or e-cigarette, you are left with a different product and different toxicity effects. The various flavours are also an issue: Many compounds not listed on labels have been identified in e-liquids, some of which turn into known toxicants when heated and aerosolized. Several hazardous compounds have been found to be formed including formaldehyde, acetaldehyde, and acrolein, which are known carcinogenic toxicants (Eaton 2018). And yes, these cause oxidative stress as well.”

Does Vaping Affect Sperm & Male Fertility? I Conceive Health

What effect does vaping have on male infertility? Does it lower sperm count, sperm motility, sperm viability, and more? Find out today!

conceivehealth.com

 

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“A father's exposure to nicotine may cause cognitive deficits in his children and even grandchildren, according to a study in mice publishing on October 16 in the open-access journal PLOS Biology by Pradeep Bhide of Florida State University in Tallahassee and colleagues. The effect, which was not caused by direct secondhand exposure, may be due to epigenetic changes in key genes in the father's sperm.”

Father's nicotine use can cause cognitive problems in children and grandchildren: Mouse study implicates epigenetic changes in paternal sperm DNA

A father's exposure to nicotine may cause cognitive deficits in his children and even grandchildren, according to a new study. The effect, which was not caused by direct secondhand exposure, may be due to epigenetic changes in key genes in the father's sperm.

www.sciencedaily.com

 

[ecstatichamster]

Dr. Peat was never very enthusiastic about tobacco, saying that a little for an older person may be helpful, to paraphrase. I think I agree with that. I think some occasional cigar smoking or pipe smoking can be very relaxing and there is merit to it. But not habitually consuming.