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  1. aliml

    PUFA-induced metabolic enteritis as a fuel for Crohn's disease

    https://pubmed.ncbi.nlm.nih.gov/35031299 Background & aims: Crohn's disease (CD) globally emerges with Westernization of lifestyle and nutritional habits. However, a specific dietary constituent that comprehensively evokes gut inflammation in human IBD remains elusive. Here, we aimed at...
  2. haidut

    Blocking Endotoxin (LPS) May Reverse/cure Diabetes Type I

    Yet another study demonstrating the key role of endotoxin in the pathology of perhaps the most widespread chronic disease - diabetes. The study below discovered that the proliferation of the insulin-producing beta-cells in the pancreas is controlled almost entirely by the TLR4/TLR2 receptor...
  3. haidut

    Bacterial Lipids (endotoxin), Not Cholesterol, May Be A Cause Of CVD

    The role of endotoxin (and TLR) in cardiovascular disease (CVD) is probably well-known by most people on this forum. Peat rarely writes on a topic without mentioning either endotoxin or keeping the gut clean as one of the main paths to good health. The role of cholesterol is finally getting to...
  4. P

    Saturated Fatty Acids,including Lauric Acid Activates TLR4

    Some studies showing coconut oil has anti stress effects,but this one surprised me! Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner The saturated fatty acids...
  5. haidut

    Serotonin Production In The Gut Is Fully Controlled By Microbiome

    A year and a half ago I posted about a study which found that serotonin production in the gut depends on the bacteria living in the colon. Serotonin Production (gut) Depends On Bacteria At the time, the study was considered controversial as the role of microbiome in serotonin production was...