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mineralocorticoid

  1. md_a

    RENIN-ANGIOTENSIN-ALDOSTERONE SYSYTEM And HAIR LOSS PROCESS

    I think excess cortisol-aldosterone- mineralocorticoid activation trough angiotensin system are main players in balding by cytokine activation and progressing to fibrosis. Focusing on TGF-β₁, which shuts off the anagen phase of the hair cycle, and 11β-HSD₁ expression should fix to the problem...
    • md_a
    • Thread
    • aldosterone angiotensin cytokines fibrosis hair loss mineralocorticoid progesterone renin tgf-b1
    • Replies: 127
    • Forum: Scientific Studies
  2. haidut

    Cortisol And Aldosterone Cause Vascular Calcification

    In one of his newsletter circa 2015, Ray wrote about the role of aldosterone in heart failure, heart attacks, shock, and edema. He conjectured that aldosterone antagonists would one day be recognized as therapeutic for these conditions. Almost all types of heart disease start with vascular...
    • haidut
    • Thread
    • aldosterone cortisol cvd dhea emodin heart disease mineralocorticoid pregnenolone progesterone receptor salt sodium vascular calcification
    • Replies: 39
    • Forum: Scientific Studies
  3. haidut

    Pregnenolone Is A Potent Aldosterone Antagonist (antimineralocorticoid)

    Ray has written a number of articles on the hypertension, heart and kidney failure, eclampsia, and CVD in which he describes the central role of aldosterone in the pathogenesis of these conditions. Aldosterone antagonists (antimineralocorticoids - e.g. spironolactone, itself a pregnenolone...
    • haidut
    • Thread
    • aldosterone antagonist inhibitor mineralocorticoid pregnenolone
    • Replies: 10
    • Forum: Scientific Studies
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