I read this whole thread briefly and this is just my two cents, but do you realize that your acne maybe related more towards high estrogen then low zinc? I mean possibly taking that much zinc probably boosts your metabolism even more thus, requiring the need for B's and A even higher. perhaps something like 4oz liver and 2-3 cans of oysters per week would work better. sometimes less is more.. What about thyroid, have you tried small amounts of that? what about increasing protein and B vitamins (potatoes/meat are both high in B's)? both are necessary to detox estrogen. Maybe you need higher amounts of both. carrot salads for endotoxin, gut inflammation.... Idk this is coming from a guy who hasnt figure out his own problems, but those are just my thoughts after reading this thread....