Pointless
Member
- Joined
- Apr 13, 2016
- Messages
- 945
I just got some benzocaine 99+% purity powder in the mail from Amazon. I took a tiny crumb, probably 1/50th - 1/100th of a teaspoon. I felt some numbness in the throat for about 30 minutes to an hour, and feeling a pretty dramatic drop in stress. I'm feeling relaxed, a bit sleepy, breathing deeply like I just took some baking soda or acetazolamide, and warm in the hands. I'm interested whether this will have permanent effects on my mood, general inflammation, or digestion.
I do have some questions about the caine drugs from a Peaty perspective and wondered if anyone had any insight on these things.
Benzocaine blocks the voltage-gated sodium channels. Are these the so-called ion pumps that Ling doubts the existence or importance of? If they influence sodium metabolism, would supplementing salt make benzocaine more effective?
Large doses of benzocaine can cause methemoglobinemia, a change in iron's state within red blood cells that prevents oxygen transport. How does this influence iron metabolism, from a Peaty perspective? If I have very low ferritin, am I in greater danger of these side effects? What dose might be dangerous in this regards? Would long-term dosing increase the problem? My nail beds are quite pink with no sign of blue, btw.
Anyone that has an other insights or experiences is free to share them here, because I think this is an area that is very worthy of experimentation, given Peat's respect for these substances.
"RP: These studies have been done in many different ways. But I've had several sort of random experiences with both Procaine and Lidocaine that were really just amazing to me. For example, a girl with life time terrible eczema, red and scaly all over; she put a hand full of I think it was rubbing alcohol mostly with some Novocaine in it and stroked it up her shin. And with at same speed that her hand moved up her shin a wave of normal looking skin appeared right behind it. And it stayed that way. And I've seen people with terrible burns. If they could get it on in the first minute or so the burn stopped and didn't develop. It has anti-histamine, anti-serotonin effects, stopping inflammation in its tracks. But what it´s doing — all of these well known anti-inflammatory things are also undoing the limiting and harmful genetic changes that are caused by injury.
HD: Yeah, it's almost as if the perception of pain itself accelerates the damage and the inflammation from that which caused the pain and inflammation in the first place. It's like a…
RP: The nerves increase the release of the inflammatory materials."
I do have some questions about the caine drugs from a Peaty perspective and wondered if anyone had any insight on these things.
Benzocaine blocks the voltage-gated sodium channels. Are these the so-called ion pumps that Ling doubts the existence or importance of? If they influence sodium metabolism, would supplementing salt make benzocaine more effective?
Large doses of benzocaine can cause methemoglobinemia, a change in iron's state within red blood cells that prevents oxygen transport. How does this influence iron metabolism, from a Peaty perspective? If I have very low ferritin, am I in greater danger of these side effects? What dose might be dangerous in this regards? Would long-term dosing increase the problem? My nail beds are quite pink with no sign of blue, btw.
Anyone that has an other insights or experiences is free to share them here, because I think this is an area that is very worthy of experimentation, given Peat's respect for these substances.
"RP: These studies have been done in many different ways. But I've had several sort of random experiences with both Procaine and Lidocaine that were really just amazing to me. For example, a girl with life time terrible eczema, red and scaly all over; she put a hand full of I think it was rubbing alcohol mostly with some Novocaine in it and stroked it up her shin. And with at same speed that her hand moved up her shin a wave of normal looking skin appeared right behind it. And it stayed that way. And I've seen people with terrible burns. If they could get it on in the first minute or so the burn stopped and didn't develop. It has anti-histamine, anti-serotonin effects, stopping inflammation in its tracks. But what it´s doing — all of these well known anti-inflammatory things are also undoing the limiting and harmful genetic changes that are caused by injury.
HD: Yeah, it's almost as if the perception of pain itself accelerates the damage and the inflammation from that which caused the pain and inflammation in the first place. It's like a…
RP: The nerves increase the release of the inflammatory materials."