Such_Saturation
Member
- Joined
- Nov 26, 2013
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- 7,370
Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
<<although it is attractive to speculate that the sebaceous gland hypertrophy and elevated levels of 15-dPGJ2 observed in both human AGA and mouse K14-Ptgds model might be related, the causal connection is unclear. Despite this, a growing literature correlates elevated 15-dPGJ2 levels with sebaceous hyperplasia, such as in acne. Given the common requirement of circulating sex hormones and common histology of sebaceous hyperplasia, acne and AGA may have overlapping pathogeneses.>>
<<although it is attractive to speculate that the sebaceous gland hypertrophy and elevated levels of 15-dPGJ2 observed in both human AGA and mouse K14-Ptgds model might be related, the causal connection is unclear. Despite this, a growing literature correlates elevated 15-dPGJ2 levels with sebaceous hyperplasia, such as in acne. Given the common requirement of circulating sex hormones and common histology of sebaceous hyperplasia, acne and AGA may have overlapping pathogeneses.>>