Since 2002, 99%+ of Alzheimer Disease trials have failed

haidut

Member
Forum Supporter
Joined
Mar 18, 2013
Messages
19,798
Location
USA / Europe
This is another clue suggesting that the underlying theory used to understand and treat diseases such as AD and cancer is probably not sound. A lower, but still abysmal number of failures was found for cancer trials.

http://www.bbc.com/news/health-28125265

"...There is an urgent need to increase the number of potential therapies being investigated, say US scientists. Only one new medicine has been approved since 2004, they report in the journal Alzheimer's Research & Therapy. The drug failure rate is troubling and higher than for other diseases such as cancer, says Alzheimer's Research UK. Dr Jeffrey Cummings, of the Cleveland Clinic Lou Ruvo Center for Brain Health, in Las Vegas, and colleagues, examined a public website that records clinical trials. The authors of the study highlight a worrying decline in the number of clinical trials for Alzheimer's treatments in more recent years. Between 2002 and 2012, they found 99.6% of trials of drugs aimed at preventing, curing or improving the symptoms of Alzheimer's had failed or been discontinued. This compares with a failure rate of 81% for cancer drugs."
 

burtlancast

Member
Joined
Jan 1, 2013
Messages
3,263
From your article:
"There is a danger that the high failure rates of trials in the past will discourage pharmaceutical companies from investing in dementia research.

"The only way we will successfully defeat dementia is to continue with high quality, innovative research, improve links with industry and increase investment in clinical trials."


Get ready for the proverbial "War against Alzheimer", to be followed soon by the "War against unproven therapies"...
 
OP
haidut

haidut

Member
Forum Supporter
Joined
Mar 18, 2013
Messages
19,798
Location
USA / Europe
burtlancast said:
From your article:
"There is a danger that the high failure rates of trials in the past will discourage pharmaceutical companies from investing in dementia research.

"The only way we will successfully defeat dementia is to continue with high quality, innovative research, improve links with industry and increase investment in clinical trials."


Get ready for the proverbial "War against Alzheimer", to be followed soon by the "War against unproven therapies"...

Yep, Big Pharma is probably thinking "if we are failing so miserably, we can hopefully cause misdirection by pointing out how many people have died by trying alternative therapies".
I think NIH has a page of "dangerous" therapies for cancer. For a long time they had aspirin listed in there, but as of May 2014 I notice that they have removed it. Maybe it is a sign that the evidence for aspirin cannot be ignored any more, or at least aspirin can no longer be listed as "dangerous" therapy.
 

Similar threads

Back
Top Bottom