Zafirlukast Decreases Heart's Serotonin Levels

[Adrenaline]

For those who do not know Zafirlukast is an anti-asthma drug. (leukotriene receptor antagonist) Study shows that zafirlukast protects against adrenaline + decreases heart's serotonin content by %19.

[Influence of zafirlucast on the content of leukotrienes, biogenic amines and prostaglandins in blood and myocardium in epinephrine-induced heart inj... - PubMed - NCBI

Two injections of zafirlucast had a favorable impact on serotonin content in the myocardium (this parameter decreased by 19%), promoted a decrease in adrenaline content and normalization of the norepinephrine/epinephrine ratio