Why testosterone, dht makes me more fatigue?


Jul 28, 2018
My testosterone is on low side, DHT is just little below border. I tried in past 10 years many things. What I don't understand is this:

When I tried 7 years ago testosterone gel I felt a nice boost in libido instantly in hour or before, no doubt. Also got morning woods. Now if I try testosterone gel or DHT drops I don't feel anything at all, absolutely nothing. And after 2 days of using it I feel more fatigue.

I was thinking if the problem is about cortisol. But my cortisol is not so bad. I even tried adding hydrocortisone just to see if cortisol is the problem.

Could be something about dopamine/serotonine balance? Maybe boosting dopamine is causing serotonin levels to be too low?

Rave re-peat

Jan 29, 2021
Hmm have you done some blood tests generally? Like whats your B12, vitamin D, Zinc and Iron levels like? Anabolics increases blood synthesis if you already struggling with fatigue it could be something like iron deficiency. Your body might not have enough iron to produce the extra blood. Id look into that if I where you.


May 1, 2016
A finding in those with higher testosterone levels is more tiredness after meals. Sorry can't find studies at the moment. My speculation: could be that the higher androgens response results in lower stress hormones concomitantly and signals body to sleep rather than being propped awake by cortisol and adrenaline. So perhaps allow yourself more sleep. May be similar to the universal increased sleep need which exercise typically creates as part of the recovery and hormetic/building process.


Jun 23, 2020
Could be a whole host of factors.
Exogenous androgen use decreases thyroid function on numerous levels - loss of testicular TRH, increased estradiol leading to elevated TBG and decreased peripheral T4 -> T3, etc.
Decreases in other upstream hormones like preg, prog, dhea.
Altered cortisol as you already mentioned.
Estrogen-induced increase in prolactin and serotonin.
Exacerbated sleep apnea.
Iron overload from testosterone's suppression of hepacidin.
Simply not using enough since gel has such a poor absorption, so as soon as your natural production shuts down in a month or so your levels go back to being low.
The list could go on; would need detailed bloodwork to get the proper picture.


May 16, 2018
Two reasons:

1) androgens oppose cortisol which is probably where you got your energy from all these years if your androgens are low

2) sleep is agitated and of poor quality on androgens
Similar threads
Thread starter Title Forum Replies Date
haidut DHT better (and safer) than testosterone for improving blood pressure, insulin levels Scientific Studies 16
Lokzo This Herb Increases Testosterone, DHT, Dopamine, NGF, GDNF, Neurogenesis (Cistanche Extract) Supplements, Pharmaceutical Drugs 8
cupofcoffee Cordyceps militaris Fruit Body Extract increases testosterone and DHT secretion Scientific Studies 46
Yggr Physiological Production Of Testosterone And DHT Per Day Male Issues 1
Cameron Higher Dht And Testosterone And Less Toxic Trt Male Issues 149
Momado965 Buying Bio Identical Testosterone And Dht Supplements, Pharmaceutical Drugs 16
SOMO What Happens If A Woman Takes Testosterone/DHT/Anavar/AAS? Ask For Help or Advice 3
S Is Having High DHT - Low Testosterone Good? Male Issues 27
D Study Found Positive Correlation Between Iron And Total +free Testosterone, Higher T3, DHT Scientific Studies 20
Hans The Conversion Of Testosterone To DHT Is IGF-1 Dependent Scientific Studies 25
L Has Anyone Tried Raising Testosterone Without Raising Dht? Male Issues 28
R Testosterone Suppression From Low Dose DHT? Hormones 48
ddjd Does DHT Increase Or Decrease Serum Testosterone? Ask For Help or Advice 8
cyclops DHT Vs Testosterone Safety Supplements, Pharmaceutical Drugs 55
L Creatine Increases DHT Without Lowering Testosterone Supplements 0
ecstatichamster Testosterone Replacement Therapy LOWERS DHT Levels In Men Scientific Studies 9
X3CyO The Problems With DHT And Testosterone Male Issues 21
J Natural DHT & Testosterone Maximization Through Peating Male Issues 149
haidut Oral Progesterone Increases Testosterone And DHT Scientific Studies 105
haidut Oral testosterone + vitamin E may treat NAFLD, NASH, cirrhosis in humans Scientific Studies 5
M Normal/High Testosterone but low DHEA-S Blood Work, Labs 14
cupofcoffee Trenbolone Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S Thyroid and Hormones 0
D Where to get testosterone with no prescription? Supplements 22
haidut Testosterone therapy (TRT) reverses hair loss (in women) Scientific Studies 16
Y Deeper voice in relation to testosterone levels Ask For Help or Advice 5
F My stack for testosterone, anxiety, inflammation and muscle growth: reasonable? Supplements 54
P How to extract Testosterone from water suspension? Ask For Help or Advice 8
Mito The association between testosterone, estradiol and their ratio and mortality among US men Scientific Studies 1
vetbusd Testosterone Experiment - Input wanted Blood Work, Labs 31
A Vegan diet testosterone Male Issues 9
T Aspirin and Testosterone Ask For Help or Advice 14
S Aspirin reduces testosterone and sperm count Ask For Help or Advice 89
U How to lower testosterone in women? Female Issues 17
W High DHEA but low testosterone? Blood Work, Labs 3
D Cypro Histamine2-receptor antagonism reduces testosterone and motivation? Cyproheptadine 12
Hans 7 Uncommon testosterone boosting supplements Articles & Scientific Studies 14
S DMSO & Testosterone Male Issues 1
Epistrophy Pregnenolone + Testosterone Base = All natural pain killer Experiments 24
B Help Dissolving Testosterone Base Powder Thyroid and Hormones 8
M High testosterone low libido Diet 23
Lokzo COVID‐19 pneumonia causes lower testosterone levels - PUBMED 2020 Scientific Studies 4
K This guy has basically no testosterone Male Issues 0
ddjd Testosterone agonises 11-beta-HSD-1 i.e. raising cortisol!! Ask For Help or Advice 4
B Testosterone shortens lifespan? Male Issues 10
TheBeard B Vitamins Doubled My Total Testosterone Levels Male Issues 105
Lokzo Testosterone As Well As Estrogen Increases Serotonin2A Receptor MRNA Scientific Studies 0
D Question For Testosterone Gurus Ask For Help or Advice 8
J Testosterone Thyroid and Hormones 13
Mr.Cacciatore Testosterone Cream On Penis Male Issues 5
P Testosterone Supplementation Help Male Issues 22

Similar threads