Why hypothyroidism increases cholesterol and its mechanism?

[VincentLin68]

Could Dr. Peat or the others explain
(1) why hypothyroidism increases cholesterol?; and
(2) what is its mechanism by increasing the serum cholesterol, such as increase the synthesis of cholesterol inside cells or reducing its receptors on cell membranes, etc.?

 

[j.]

Re: Why hypothyroidism increases cholesterol and its mechani

Could Dr. Peat or the others explain
(1) why hypothyroidism increases cholesterol?

Because thyroid converts cholesterol to other hormones. When there is less thyroid, less cholesterol is converted to the other hormones.

 

[pranarupa]

Re: Why hypothyroidism increases cholesterol and its mechani

Could Dr. Peat or the others explain
(1) why hypothyroidism increases cholesterol?; and
(2) what is its mechanism by increasing the serum cholesterol, such as increase the synthesis of cholesterol inside cells or reducing its receptors on cell membranes, etc.?

I don't think Ray Peat comments here unless he's using an alias.

1. metabolism slows so conversion of cholesterol to protective steroids slows.

2. The body is not a machine, there are no lipid bilayer membranes studded with receptors.

TSH-Controlled L-Thyroxine Therapy Reduces Cholesterol Levels and Clinical Symptoms in Subclinical Hypothyroidism: A Double Blind, Placebo-Controlled Trial