Why Does Eating Too Much Liver Cause Hypothyroidism?

Discussion in 'Organ Meat' started by Logan-, Apr 26, 2019.

  1. Logan-

    Logan- Member

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    Ray Peat has talked about this a lot.

    Here's an example from his emails:


    What is the mechanism behind this effect?
     
  2. milkboi

    milkboi Member

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    Logan-

    Logan- Member

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    Thanks.
     
  4. BigChad

    BigChad Member

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  5. Mr. God of Cars

    Mr. God of Cars Member

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    Why would vitamin A do that?
     
  6. lampofred

    lampofred Member

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    It is highly unsaturated plus is carried on the same transporter that thyroid hormone is carried on.
     
  7. Mr. God of Cars

    Mr. God of Cars Member

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    Unsaturated fats? If not, what does it mean when a molecule is unsaturated?
     
  8. lampofred

    lampofred Member

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    To be honest I don't know what it means for a vitamin to be unsaturated. In terms of PUFA, I understood it as unsaturated = unstable chemical bonds so prone to rancidity upon exposure to heat, but I don't think vit A is toxic in the same way that PUFA is even though it's unsaturated.

    But it is carried on the same protein that thyroid is carried on, so an excess of vit A would mean no remaining space for thyroid hormone to get transported in the body and will cause temporary hypothyroidism in that sense.
     
  9. milkboi

    milkboi Member

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    It means that a molecule does not have the maximum possible amount of hydrogen atoms relative to the amount of carbon atoms.
     
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