Why does cyproheptadine give me cold hands and feet?

PaRa

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Nov 18, 2019
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anti histamine and anti acetylcholine, both promoting heat and blood flow, and both antagonizing cortisol and epinephrine
 

Hans

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Aug 24, 2017
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Histamine promotes blood flow and thermogenesis, so lowering that can cause the catecholamines to increase which causes vasoconstriction and cold hands and feet. Thyroid is most likely low.
 

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