Why can insulin resistance be consequence of thyroid dysfunction?

hmac

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Jun 9, 2015
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In seeking to educate myself I came across this study which makes some confusing assertions as to the effect of thyroid hormone

http://www.hindawi.com/journals/jtr/2011/152850/

Amongst some positive effects it is also claimed that thyroid can:
- decrease glycogen storage
- increase fatty acid oxidation
- cause insulin resistance
- increase HIF1

Is it simply that this is what happens in the absence of adequate fuel, like with caffeine? Is it more complex? Or is it, simply, wrong?

I would be very grateful if someone better informed than me would elucidate!
 

Mittir

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Feb 20, 2013
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I just read the abstract and it seems right. In hypothyroidism stress hormones are high, which blocks
glucose oxidation and in hyperthyroidism ,it is similar to caffeine, increased demand for fuel
led to increased stress hormone and muscle breakdown.

RP has also mentioned that diabetic are hypothyroid as thyroid function
depends on glucose metabolism.
 
OP
H

hmac

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Joined
Jun 9, 2015
Messages
141
Mittir said:
post 107095 I just read the abstract and it seems right. In hypothyroidism stress hormones are high, which blocks
glucose oxidation and in hyperthyroidism ,it is similar to caffeine, increased demand for fuel
led to increased stress hormone and muscle breakdown.

RP has also mentioned that diabetic are hypothyroid as thyroid function
depends on glucose metabolism.

Thanks Mittir,
Yeh, I should have specified that it was the hyperthyroid states that had been seen to cause the things i listed, and that was what was surprising but it does seem to be the increased fuel requirement causing stress cascade etc.
 
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