Whole blood minerals

[Belsazar]

Hello,

I would need help with interpretation of whole blood minerals.

Calcium from whole blood mineral shows a low value 49 mg/l (range 49.9-59.5). How reliable is that calcium parameter?

Another value that bothers me is a elevated Manganese (also from whole blood). Since my liver has some troubles and it is secreted via bile, I suspect it comes from that issue. But how dangerous is that? Any input appreciated. Some say (https://www.inflammatio.de/fileadmin/user_upload/inflammatio/OF-Vorträge/2017/2017_01_11_Mangan.pdf) coffee and tea are a high source of manganese and that high levels are neurotoxic, so I am a bit worried.

 

[Perry Staltic]

How elevated is the Mn?

 

[Belsazar]

Manganese was 18 µg/l (range 5.0-11.1)

 

[Perry Staltic]

Manganese was 18 µg/l (range 5.0-11.1)

I'm reading normal range going as high as 16.5 mcg/l, so if 18 is elevated it doesn't seem by much. Maybe cut down on Mn rich foods a bit. Usually the people who can get in trouble with Mn are people like welders, potters (Mn glazes) and Mn mine workers who breathe in Mn rich fumes/dust constantly.

Manganese (whole blood) | Healthmatters.io

The general population is exposed to manganese through consumption of food and water, inhalation of air, and dermal …

healthmatters.io

 

[Belsazar]

I'm reading normal range going as high as 16.5 mcg/l, so if 18 is elevated it doesn't seem by much. Maybe cut down on Mn rich foods a bit. Usually the people who can get in trouble with Mn are people like welders, potters (Mn glazes) and Mn mine workers who breathe in Mn rich fumes/dust constantly.

Manganese (whole blood) | Healthmatters.io

The general population is exposed to manganese through consumption of food and water, inhalation of air, and dermal …

healthmatters.io

Thanks, thats good to hear. But the lab stated they changed the method and therefore changed the reference range. Due to work I also came in contact with Mn a few months ago, thats why I got worried. But I am not constantly exposed. I will definitely keep an eye on it in the future.

 

[Perry Staltic]

Thanks, thats good to hear. But the lab stated they changed the method and therefore changed the reference range. Due to work I also came in contact with Mn a few months ago, thats why I got worried. But I am not constantly exposed. I will definitely keep an eye on it in the future.

Curious, what kind of contact?

 

[Belsazar]

Lab chemicals. Usually I am careful, but who knows.

 

[Perry Staltic]

You may have gotten dosed with some, but doesn't look like much. Have never done so for Mn, but took chelation pills for mercury once, so if it really concerns you maybe you could look into that possibility for Mn.

 

[redsun]

Hello,

I would need help with interpretation of whole blood minerals.

Calcium from whole blood mineral shows a low value 49 mg/l (range 49.9-59.5). How reliable is that calcium parameter?

Another value that bothers me is a elevated Manganese (also from whole blood). Since my liver has some troubles and it is secreted via bile, I suspect it comes from that issue. But how dangerous is that? Any input appreciated. Some say (https://www.inflammatio.de/fileadmin/user_upload/inflammatio/OF-Vorträge/2017/2017_01_11_Mangan.pdf) coffee and tea are a high source of manganese and that high levels are neurotoxic, so I am a bit worried.

Manganese toxicity can cause high prolactin, which is due to antagonizing iron too much (since iron is the metal necessary for dopamine). And high prolactin is bad for hormones and health as a whole. If you got exposed in a lab that could be why. Also if you are already iron deficient, you will absorb more manganese from your food. You may need iron thats why manganese is out of range and/or because you were exposed to too much manganese.

Prolactin is a peripheral marker of manganese neurotoxicity

Excessive exposure to Mn induces neurotoxicity, referred to as manganism. Exposure assessment relies on Mn blood and urine analyses, both of which show poor correlation to exposure. Accordingly, there is a critical need for better surrogate biomarkers ...

www.ncbi.nlm.nih.gov

 

[Belsazar]

Manganese toxicity can cause high prolactin, which is due to antagonizing iron too much (since iron is the metal necessary for dopamine). And high prolactin is bad for hormones and health as a whole. If you got exposed in a lab that could be why. Also if you are already iron deficient, you will absorb more manganese from your food. You may need iron thats why manganese is out of range and/or because you were exposed to too much manganese.

Prolactin is a peripheral marker of manganese neurotoxicity

Excessive exposure to Mn induces neurotoxicity, referred to as manganism. Exposure assessment relies on Mn blood and urine analyses, both of which show poor correlation to exposure. Accordingly, there is a critical need for better surrogate biomarkers ...

www.ncbi.nlm.nih.gov

Well, I just weighed some in, so I actually doubt i have inhaled much if any at all. I might cut back on oats and tea ...
Prolactin is not elevated, iron & ferritin are also in range.

It seems in liver disease, manganese excretion is impaired and i was diagnosed with a fatty liver (no clue why, but probably Vitamin A related) recently ...

 

[Belsazar]

Just some infos on mineral analysis from whole blood:

https://www.imd-berlin.de/fileadmin/user_upload/Diag_Info/298_Mineralstoffanalyse_im_EDTA_Vollblut_MEA.pdf

Figure1: shows how certain minerals are distributed. It seems Manganese, Zink, Magnesium are mostly in blood cells and an analysis from plasma/serum would not detect the correct levels.