So there's been a fair amount of talk about "receptor density" on the forums lately, with @haidut posting some studies showing that anti-serotonin drugs like cyproheptadine decrease the 5-HT (serotonin) receptor density in the brain. What exactly does this mean? It seems Ray Peat is not fond of talking about "receptors"; he doesn't believe in their existence?
If a drug lowers receptor density of serotonin, does it mean that less serotonin will be able to provoke a greater response, or the opposite (more serotonin is needed to induce "high serotonin symptoms").
Do we want a high or low receptor density of dopamine? of serotonin?
If a drug lowers receptor density of serotonin, does it mean that less serotonin will be able to provoke a greater response, or the opposite (more serotonin is needed to induce "high serotonin symptoms").
Do we want a high or low receptor density of dopamine? of serotonin?