Good, thiamine has helped me tremendously as well but I believe @mostlylurking aka mostlythiamine covered that subject superbly!i cant lie reading this felt nice, lol. i shouldnt think negative like that
Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Click Here if you want to upgrade your account
If you were able to post but cannot do so now, send an email to admin at raypeatforum dot com and include your username and we will fix that right up for you.
Good, thiamine has helped me tremendously as well but I believe @mostlylurking aka mostlythiamine covered that subject superbly!i cant lie reading this felt nice, lol. i shouldnt think negative like that
Here are some links to information about thiamine that I found helpful:Wow, lots to digest here, I have Dr Clarks B1 and i did feel like it helped when i was taking it last year. This year it started causing stress responses. I just took some earlier and got a "reaction" although it did make my temperature go up to 99 degrees rather than my usual afternoon temp of 98.8 so it probably did give me a boost, but I still have head pressure and neck muscle tension from the slight reaction. I will see if i sleep well tonight though.
I took doctor (!) prescribed 5-htp for 10 years; before that Prozac for 2 years. I had my appendix out 2012. I stopped the 5-htp November of 2014. I was very sick at that time and found Ray Peat's website then.Can you think back and try to remember if anything happened the month or two before this time? Did you have any illnesses? Did you take any antibiotics?
no but i did start keto and remember my heart beating through my chest at night months before this happened. I was so ignorant to health that i just ignored it. Last time i took antibiotics was in 2017 when i had my appendix taken out which i know is related to high serotonin. The 5htp i was taking i had been taking for years, i think that has a lot to do with what happened
oops.How often were you taking this pill? Once or twice a week?
50,000 iu Daily for about 2 weeks
Leaky gut?
I need to learn more about this
Watch those videos too. I think you will find them helpful.About blood tests: Thiamine Deficiency Testing: Understanding the Labs- Hormones Matter
Definitely going to do this.
Did the dentist use a dental dam when they removed the amalgam fillings?i did when it first happened, after the first year i got them taken out and replaced with the white fillings. As for heavy metals i dont think so, i did work construction and sanded to the point of coughing up blood but that was years before all this. i was a heavy drinker a couple years before my first attack which does deplete thiamine.
im on it, thank you so muchHere are some links to information about thiamine that I found helpful:
https://www.youtube.com/c/EONutrition/playlists Elliot has a playlist with his videos about thiamine. Take a look, perhaps starting with the oldest one and working your way forward would be the way to go.
You searched for Dr Derrick Lonsdale - Hormones Matter This is a list of the articles written by Dr. Derrick Lonsdale; these are very good. Dr. Chandler Marrs has informative info on thiamine too; this is her website. I prefer following Dr. Ray Peat for information on hormones and diet though.
HDT Therapy This is Dr. Costantini's website. He treated several thousand Parkinson's Disease successfully with thiamine hcl. Lots of excellent information here. Read the Therapy page, also the FAQs here: FAQ. Also spend the time to watch the videos of Dr. Costantini's patients here: Videos Parkinson's Patients before and after treatment - Ultima Edizione.Eu These are very short; most of them are less than a minute.
Please note that Dr. Costantini advised to take all the day's thiamine before 3:00pm because otherwise it will hamper sleeping. If taken before 3:00pm, it improves sleep.
I took doctor (!) prescribed 5-htp for 10 years; before that Prozac for 2 years. I had my appendix out 2012. I stopped the 5-htp November of 2014. I was very sick at that time and found Ray Peat's website then.
oops.
How Low Thiamine Can Thin Villi: Old Research Rediscovered and its Clinical Significance in Celiac Disease
What was the trigger for celiac disease, of course gluten played a part, but what in my past history put me over the edge? What had changed? Did the doctors know so little about the trigger for celiac disease that it was only now becoming clinically identifiable?www.celiac.com
I had years of life with many many food sensitivities because I had leaky gut. I'm good now. I still can't eat gluten without serious regret but most people have trouble with gluten.
alsoThiamine Deficiency - A Potential Cause of SIBO and other Gut Dysfunction?
Thiamine deficiency - A consequence or cause of SIBO? In the previous article, I explained how SIBO and gut dysbiosis could increase the risk of thiamine deficiency. Thiamine's uptake from the gut may be disrupted in cases of malabsorption, which is a common feature of SIBO. The composition of...www.eonutrition.co.uk
Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency - PubMed
and
Altered expression of tight junction proteins and matrix metalloproteinases in thiamine-deficient mouse brain - PubMed
Wernicke's encephalopathy (WE) in humans is a metabolic disorder caused by thiamine deficiency (TD). In both humans and experimental animals, TD leads to selective neuronal cell death in diencephalic and brainstem structures. Neuropathologic features of WE include petechial hemorrhagic lesions...pubmed.ncbi.nlm.nih.gov
Watch those videos too. I think you will find them helpful.
The non use of a dental dam would indicate that the dentist didn't know what the hell he was doing and exposed you to a LOT more mercury via the removal of the fillings without safety precautions. It happened to me. As my mercury amalgams crumbled (due to absorption of mercury from the amalgam), my dentist would remove them and replace them with gold inlays. This set up an electrical current in my mouth which expedited the failure of more of the mercury amalgams in my mouth. Rinse. Repeat.im on
im on it, thank you so much
Did the dentist use a dental dam when they removed the amalgam fillings?
unfortunately i don't know, i was so uncomortable i just closed my eyes and waited for it to be over? What would the use or non use of one indicate?
I posted the link to this article above. Here's the link again: Thiamine Saves — Mercury Free Kidsim on
im on it, thank you so much
Did the dentist use a dental dam when they removed the amalgam fillings?
i googled it and they didnt use anything like that
I have similar 'attacks' though it fits the panic attack symptoms more. Cypro doesn't completely stop it if I'm super high adrenaline, but over the course of several days I notice I don't have the attacks anymore. So it isn't like taking Xanax but it's a useful tool to lower stress hormones in emergency situations. Progesterone is acting like an anesthetic sounds like as it raises relaxing neurotransmitters, so you are using it much the same as Xanax but without the dependency.My vitamin D levels jumped up to 47 after a while and when i stopped taking vitamin d it went back down to about 15 when i checked in january, for some reason just last month it has gone up to 24 although i have not touched the sun or supplemented at all. Im guessing its from this new way of eating. But my vitamin d levels seem to have zero impact on my condition anymore. Also sunlight is not the only thing that gives me this reaction, eating a steak can cause a similar reaction just not as strong. I live in a country where i can buy cypro at the store and have it in the stash. It did help me sleep but i never felt powerful relief from it, i feel much more relief from progesterone and activated charcoal with OJ and salt when i get these reactions.
Bag breathing, sugar, and salt... Along with the frame of mind that this too shall pass...I have similar 'attacks' though it fits the panic attack symptoms more. Cypro doesn't completely stop it if I'm super high adrenaline, but over the course of several days I notice I don't have the attacks anymore. So it isn't like taking Xanax but it's a useful tool to lower stress hormones in emergency situations. Progesterone is acting like an anesthetic sounds like as it raises relaxing neurotransmitters, so you are using it much the same as Xanax but without the dependency.
If I understand correctly, serum thiamine is not great for measuring levels. Whole blood thiamine pyrophosphate might be a little better and ETKA test.is this too high thiamine?
Exam Result Status Collection* Time* Last Update THIAMIN (VITAMIN B1), WB Abnormal [1] Final result Aug 2, 2022 1504 Aug 2, 2022 1504
Component Value Ref Range & Units Status Thiamin (Vitamin B1), WB 259 70 - 180 nmol/L Final
Yep, the only way thru is to know it passes especially if you don't start fearing a heart attack or going crazy. Once you start thinking those thoughts it progresses to full blown panic.Bag breathing, sugar, and salt... Along with the frame of mind that this too shall pass...
50.000 (daily) for one week of Vit D. Huge!! With much less than that, I had to go to ER. Had " reaction" cause my calcium diet was low, more than a decade probably. Keep with good nutrition, don't stress your body. It will calm down. Could supplement with shell powder calcium.I understand that most people will doubt many things in this story, which is part of the reason it's hard to get help. Most doctors simply don't believe me, I'm convinced most people who hear this won't believe it. So please humor me and just pretend this is all true and accept that maybe freak occurrences like this do happen, and if you were in this situation, what would you do?
Ill try to write a quick version of this. In April of 2020 it all started with a powerful sudden case of restless leg syndrome in my right leg which was also felt in my right arm and sometimes my whole body. It was a horrible month until i found i was vitamin d deficient and upon taking prescribed 50,000iu of vitamin d I felt incredible relief. I continued taking 50,000iu for about a week and also took k2 and magnesium but was also taking loratadine for allergies and supplements with 5ht for sleeping problems. One night at 9pm i had a full on attack of some sort that lasted for 4 hours and fits the description of serotonin syndrome, yet i really have no confidence to say what it actually was. (super cold inside, body shaking, nausea, diarrhea, distorted vision, tinnitus on 1000 super loud and tense muscles all over, and the feeling that electricity was running through my brain and my heart about to bust open through my chest). I thought i was living the last minutes of my life the whole time, but after taking an ungodly amount of my sleeping supplement, eventually i fell asleep. The next night, after being reassured vitamin d couldn't hurt me, i took another 50,000iu pill and that night at the same time i had the same attack, this time i went to the ER. (I'm not blaming the vitamin d, i have no clue why it happened) They connected me to machines that monitor my brain and heart and showed me that the machine said absolutely nothing was wrong with either. they gave me a number to a psychiatrist and some xanax seemed to help a little but the damage was done. Now every single day i would get a slighly less intense version of this attack. i stopped taking vitamin d and after about a month i started to feel normal again. This was the beginning of my decline. Having no clue about anything health-related i started looking for answers online. Nothing i did gave me relief, i had no clue that what i put in my body could be causing it and thought only something i could put in my body would be able to fix it.
I lived this way for 9 months, having intense reactions randomly on a daily basis clueless as to why. Fighting suicidal thoughts daily. Went to south america and decided the sun could heal me. Thats when i realized the sun was one of the things that was causing these powerful reactions. I found this interesting because it was high vitamin d that i took initially when this all started. My 3rd attack happened 9 months later when i went under that powerful sun and had a delayed reaction. After about an hour under the sun, it wasn't until 10 pm when i was awakened from my sleep with the same exact attack i had on day 1. There is no question that the same thing just happened from the sun, that happened the day i took all that vitamin d and loratadine. I finally found Ray Peat forums after 9 months of looking for answers, came across the FPS course and it was the first time I had an idea of what was going on. Learning how to eat metabolically and avoid stress responses was a life-saving experience. I still have no clue what was wrong with me, but by paying attention to how things affected me, i quickly found that most proteins gave me a horrible reaction. I say reaction because these are not normal stress responses, the reactions are smaller versions of the full-fledged attack I had on day one.
So after a lot of trial n error, i found that most of what i was eating was causing these reactions. Even many supplements give me a powerful reaction. Calcium carbonate messes me up pretty bad. Most protein will give me a week-long reaction. I can only eat great lakes gelatin and only with a high amount of fresh OJ to avoid a stress response and Parmigiano Reggiano is my main source of fat except for when i have the carrot salad with coconut oil which does not cause reactions so i eat it daily. I finally reached the point where i can avoid reactions and now the only things i can eat are fresh squeezed OJ, cheese, and gelatin and coffee with honey. The only supplements i can use without a stress response is Solban from idea labs rubbed all over my gut since i gained 60 pounds being that the only thing that can calm my stress responses are massive amounts of OJ, but the solban does a great job of heating me up. It seems like anything i put in my stomach will cause a powerful reaction. Last time i tried even 400iu of vitamin d oil i had a weeklong reaction. Even vegetable broth of spinach and kale that i tried gave me a reaction. I believe tryptophan and calcium are causing reactions. The good news is my brain is working again and im able to work but my energy is still super limited, i can't be on my feet for more than a couple of hours without a stress response if I don't have enough OJ. I can get away with activity, but only with a bottle of OJ with me constantly feeding me sugar.
My brain is doing better today because i can go longer without a reaction to let my mind heal. But the bad news is that it feels like a window is closing on me. it feels like as time goes by, i become more reactive to more things. I used to be able to drink milk, supplement DHEA, have bone broth, and all the stuff i needed to heal, over time my body started reacting badly to those too. This is the part that scares me the most. By avoiding reactions my mind does heal, but my body seems to slowly change for the worse, not better.
oh and here is an interesting fact, when i get these reactions strong enough, they operate completely independent of my blood sugar and metabolism. The FPS course did a great job of teaching me how to support my thyroid function and balance blood sugar and avoid harmful substances, but when i get a powerful reaction, it doesn't matter how good my temperature is, the serotonin-like feelings just continue, even if my pulse and temp are perfect. I know it isn't adrenaline because of what i am consuming, the science says that my thyroid is functioning well.
And there lies the mystery, NOBODY even has a clue as to what could be the issue. my blood work is mostly normal except for high eosiniphilios and lactic acid. most stuff is normal. 17 doctors couldn't help me and 5 sent me to a psychiatrist. They bring up stuff like anxiety and fear of the sun, no, I do not suffer from any social fear, I love people, I love the sun *and enjoyed it on a tropical vacation only months before this happened., I am not seeking attention. Something happened to me and it may be a one-in-a-million case. Its been 2 and a half years and thanks to my high temps im able to maintain i can keep a positive mind and not really get depressed.
its been 2 and a half years now. I live indoors during the day and only go out at night and have to bring my OJ and cheese everywhere i go along with progesterone and activated charcoal which seem to be the only things that help me find relief from these strong reactions along with the OJ. I have to avoid sun exposure even through glass windows it can cause reactions. But i am worried that I'm not doing enough, this isn't going to fix itself, and I feel really embarrassed talking about it because most people just think I'm crazy because this doesn't fit anybody's medical expertise, but im done feeling embarrassed, im desperate and i have to find a way, i can't live like this. I just want to be able to walk down the street like normal people without being wrecked for a week with serotonin-like symptoms.
So if you were able to get through all that, i am looking for ideas. What mechanisms can i test that arent your basic bloodwork? What would you look for if this happened to you? Basic bloodwork seems pointless. I wish there were doctors like TV doctors that find a patient and try to find out what is wrong with them. I am willing to give up my life savings to fix this. But i am lost. When every doctor i talk to looks at me sideways. When everything they say will help me only gives me horrible reactions. Are there any organizations i can reach out too? Any special doctors who take on mysterious cases? I feel like im in the twilight zone sometimes. keeping high temps is preventing me from suicidal thoughts and is actually helping me find the energy to keep fighting and looking for solutions. if i can just get a professional to believe this is true, maybe I can get some direction on what to check my body for.
if you read all of this, thank you. ive been previously too embarassed and feeling stupid to ask for help. i think i have been traumatized by the look on doctors faces that i stopped asking around. but i dont have the luxury of not trying anymore, whatever this is, its not showing any signs of naturally being healed, even with the minimal diet of OJ gelatin and cheese and constantly having raised temperatures. im open to any suggestions.
What was going on in your life in April 2022 when you developed a “powerful sudden case of restless leg syndrome” in your right leg, arm and sometimes body?I understand that most people will doubt many things in this story, which is part of the reason it's hard to get help. Most doctors simply don't believe me, I'm convinced most people who hear this won't believe it. So please humor me and just pretend this is all true and accept that maybe freak occurrences like this do happen, and if you were in this situation, what would you do?
Ill try to write a quick version of this. In April of 2020 it all started with a powerful sudden case of restless leg syndrome in my right leg which was also felt in my right arm and sometimes my whole body. It was a horrible month until i found i was vitamin d deficient and upon taking prescribed 50,000iu of vitamin d I felt incredible relief. I continued taking 50,000iu for about a week and also took k2 and magnesium but was also taking loratadine for allergies and supplements with 5ht for sleeping problems. One night at 9pm i had a full on attack of some sort that lasted for 4 hours and fits the description of serotonin syndrome, yet i really have no confidence to say what it actually was. (super cold inside, body shaking, nausea, diarrhea, distorted vision, tinnitus on 1000 super loud and tense muscles all over, and the feeling that electricity was running through my brain and my heart about to bust open through my chest). I thought i was living the last minutes of my life the whole time, but after taking an ungodly amount of my sleeping supplement, eventually i fell asleep. The next night, after being reassured vitamin d couldn't hurt me, i took another 50,000iu pill and that night at the same time i had the same attack, this time i went to the ER. (I'm not blaming the vitamin d, i have no clue why it happened) They connected me to machines that monitor my brain and heart and showed me that the machine said absolutely nothing was wrong with either. they gave me a number to a psychiatrist and some xanax seemed to help a little but the damage was done. Now every single day i would get a slighly less intense version of this attack. i stopped taking vitamin d and after about a month i started to feel normal again. This was the beginning of my decline. Having no clue about anything health-related i started looking for answers online. Nothing i did gave me relief, i had no clue that what i put in my body could be causing it and thought only something i could put in my body would be able to fix it.
I lived this way for 9 months, having intense reactions randomly on a daily basis clueless as to why. Fighting suicidal thoughts daily. Went to south america and decided the sun could heal me. Thats when i realized the sun was one of the things that was causing these powerful reactions. I found this interesting because it was high vitamin d that i took initially when this all started. My 3rd attack happened 9 months later when i went under that powerful sun and had a delayed reaction. After about an hour under the sun, it wasn't until 10 pm when i was awakened from my sleep with the same exact attack i had on day 1. There is no question that the same thing just happened from the sun, that happened the day i took all that vitamin d and loratadine. I finally found Ray Peat forums after 9 months of looking for answers, came across the FPS course and it was the first time I had an idea of what was going on. Learning how to eat metabolically and avoid stress responses was a life-saving experience. I still have no clue what was wrong with me, but by paying attention to how things affected me, i quickly found that most proteins gave me a horrible reaction. I say reaction because these are not normal stress responses, the reactions are smaller versions of the full-fledged attack I had on day one.
So after a lot of trial n error, i found that most of what i was eating was causing these reactions. Even many supplements give me a powerful reaction. Calcium carbonate messes me up pretty bad. Most protein will give me a week-long reaction. I can only eat great lakes gelatin and only with a high amount of fresh OJ to avoid a stress response and Parmigiano Reggiano is my main source of fat except for when i have the carrot salad with coconut oil which does not cause reactions so i eat it daily. I finally reached the point where i can avoid reactions and now the only things i can eat are fresh squeezed OJ, cheese, and gelatin and coffee with honey. The only supplements i can use without a stress response is Solban from idea labs rubbed all over my gut since i gained 60 pounds being that the only thing that can calm my stress responses are massive amounts of OJ, but the solban does a great job of heating me up. It seems like anything i put in my stomach will cause a powerful reaction. Last time i tried even 400iu of vitamin d oil i had a weeklong reaction. Even vegetable broth of spinach and kale that i tried gave me a reaction. I believe tryptophan and calcium are causing reactions. The good news is my brain is working again and im able to work but my energy is still super limited, i can't be on my feet for more than a couple of hours without a stress response if I don't have enough OJ. I can get away with activity, but only with a bottle of OJ with me constantly feeding me sugar.
My brain is doing better today because i can go longer without a reaction to let my mind heal. But the bad news is that it feels like a window is closing on me. it feels like as time goes by, i become more reactive to more things. I used to be able to drink milk, supplement DHEA, have bone broth, and all the stuff i needed to heal, over time my body started reacting badly to those too. This is the part that scares me the most. By avoiding reactions my mind does heal, but my body seems to slowly change for the worse, not better.
oh and here is an interesting fact, when i get these reactions strong enough, they operate completely independent of my blood sugar and metabolism. The FPS course did a great job of teaching me how to support my thyroid function and balance blood sugar and avoid harmful substances, but when i get a powerful reaction, it doesn't matter how good my temperature is, the serotonin-like feelings just continue, even if my pulse and temp are perfect. I know it isn't adrenaline because of what i am consuming, the science says that my thyroid is functioning well.
And there lies the mystery, NOBODY even has a clue as to what could be the issue. my blood work is mostly normal except for high eosiniphilios and lactic acid. most stuff is normal. 17 doctors couldn't help me and 5 sent me to a psychiatrist. They bring up stuff like anxiety and fear of the sun, no, I do not suffer from any social fear, I love people, I love the sun *and enjoyed it on a tropical vacation only months before this happened., I am not seeking attention. Something happened to me and it may be a one-in-a-million case. Its been 2 and a half years and thanks to my high temps im able to maintain i can keep a positive mind and not really get depressed.
its been 2 and a half years now. I live indoors during the day and only go out at night and have to bring my OJ and cheese everywhere i go along with progesterone and activated charcoal which seem to be the only things that help me find relief from these strong reactions along with the OJ. I have to avoid sun exposure even through glass windows it can cause reactions. But i am worried that I'm not doing enough, this isn't going to fix itself, and I feel really embarrassed talking about it because most people just think I'm crazy because this doesn't fit anybody's medical expertise, but im done feeling embarrassed, im desperate and i have to find a way, i can't live like this. I just want to be able to walk down the street like normal people without being wrecked for a week with serotonin-like symptoms.
So if you were able to get through all that, i am looking for ideas. What mechanisms can i test that arent your basic bloodwork? What would you look for if this happened to you? Basic bloodwork seems pointless. I wish there were doctors like TV doctors that find a patient and try to find out what is wrong with them. I am willing to give up my life savings to fix this. But i am lost. When every doctor i talk to looks at me sideways. When everything they say will help me only gives me horrible reactions. Are there any organizations i can reach out too? Any special doctors who take on mysterious cases? I feel like im in the twilight zone sometimes. keeping high temps is preventing me from suicidal thoughts and is actually helping me find the energy to keep fighting and looking for solutions. if i can just get a professional to believe this is true, maybe I can get some direction on what to check my body for.
if you read all of this, thank you. ive been previously too embarassed and feeling stupid to ask for help. i think i have been traumatized by the look on doctors faces that i stopped asking around. but i dont have the luxury of not trying anymore, whatever this is, its not showing any signs of naturally being healed, even with the minimal diet of OJ gelatin and cheese and constantly having raised temperatures. im open to any suggestions.