Peat Party
Member
- Joined
- Jan 13, 2017
- Messages
- 8
I haven't seen this drug discussed much on this forum, other than briefly in one thread, so i thought i should create thread around it. It's relatively new, which might be the reason why there's not much discussion about it.
I wonder if anyone might have any experience with it, and also how it is in regards to safety compared to "conventional" SSRIs? The wikipedia page states that there's been incidences of sexual dysfunction with it. Might that suggest it has some effect on raising Serotonin? Vortioxetine is classified as a Serotonin Modulator and Simulator and does seem to have some inhibition on SERT. But it's also an antagonist at some 5-HT receptors.
I have tried Mirtazapine so far, previously at 30mg, now 15mg. Could the dose be too low? I've heard from a Psychiatrist i've seen, doses as high as 90mg was common. Mirtazapine has not been as effective at reducing depressive symptoms as Vortioxetine, in my experience. Mirtazapine also has weight gain as a side effect, which might not always be desired.
I wonder if anyone might have any experience with it, and also how it is in regards to safety compared to "conventional" SSRIs? The wikipedia page states that there's been incidences of sexual dysfunction with it. Might that suggest it has some effect on raising Serotonin? Vortioxetine is classified as a Serotonin Modulator and Simulator and does seem to have some inhibition on SERT. But it's also an antagonist at some 5-HT receptors.
I have tried Mirtazapine so far, previously at 30mg, now 15mg. Could the dose be too low? I've heard from a Psychiatrist i've seen, doses as high as 90mg was common. Mirtazapine has not been as effective at reducing depressive symptoms as Vortioxetine, in my experience. Mirtazapine also has weight gain as a side effect, which might not always be desired.