Vitamin D May Exacerbate Autoimmune Disease

[j.]

Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease.

Read the rest.

If it's true, my guess is that the true cause of autoimmunity in these cases might be vitamin A deficiency. Since vitamin D makes the body use vitamin A, adding vitamin D exacerbates the problem by deepening the vitamin A deficiency.

The mechanism might be that vitamin A deficiency atrophies the adrenal glands, who have the role of secreting cortisone. Cortisone regulates the immune system.

All these imply that a high level of vitamin D without adequate vitamin A could be dangerous.

 

[himsahimsa]

I have had that experience. Didn't realize at first. 6000 units D for 6 months with no supplemental vitamin A or K2 resulted in what felt like, and was diagnosed as, osteoarthritis, very painful. Subsided completely on stopping vitamin D. Now take D (cholecalciferal 3000 IU in MCT on skin) and A (fish oil + retinyl palmitate gel caps,10,000 IU) and K2 (45mg menatetranone mixed into a fat), always all 3 (if any, but most days). Now D causes no problems.

K2 in physiological dose because dealing with fluoroquinolone (re)poisoning. Will back off to ~5mg/D after a while.

That (link, above, http://www.eurekalert.org/pub_releases/ ... 040809.php) is a VERY interesting article!

 

[Steffi]

Very embarrassed. It's a scam. Sounded good.
The speaker himself organised the "international autoimmunity congress". Fascinating what believe does to people.

I came here by accident after I was once more quite down because of my autoimmune thyroiditis.
Till yesterday I thought like all the physicians I have seen so far "autoimmune causes are not known and only symptoms can be treated while conditions can only get worse over time".

This is not true! Almost all AI diseases I have heard of and more have been successfully improved and the cause is somewhat known. The cause is bacteria living inside your cells as part of the microbiome.

How the Microbiome causes Autoimmune Dysfunction :
http://www.youtube.com/watch?v=6My9p6munj8

Recovery from Autoimmune Disease
http://www.youtube.com/watch?v=YRBvYcckoWE#t=1063

results of a study with participants with all kinds of AI diseases
http://www.youtube.com/watch?v=qyoCRdX7-Yk

And here is a page with lots of ressources and a treatment plan called the Marshall Protocol (mpkb.org):
http://autoimmunityresearch.org/resources/


Anyway, sounds very interesting, but too good to be true, there is lots of critique:
http://phylogenomics.blogspot.com.au/2010/08/overselling-microbiome-award-2-marshall.html

 

[Kray]

I have had that experience. Didn't realize at first. 6000 units D for 6 months with no supplemental vitamin A or K2 resulted in what felt like, and was diagnosed as, osteoarthritis, very painful. Subsided completely on stopping vitamin D. Now take D (cholecalciferal 3000 IU in MCT on skin) and A (fish oil + retinyl palmitate gel caps,10,000 IU) and K2 (45mg menatetranone mixed into a fat), always all 3 (if any, but most days). Now D causes no problems.

K2 in physiological dose because dealing with fluoroquinolone (re)poisoning. Will back off to ~5mg/D after a while.

That (link, above, http://www.eurekalert.org/pub_releases/ ... 040809.php) is a VERY interesting article!

Saw this post by you as I was looking for help on Fluoroquinolone. My husband is on it at least for 2 weeks, unless/until primary care doc releases him from further need. Would you give me some help more specific to guarding against any side effects of Cipro? How much vit K? I have Kuinone- how much for how long? Any other supps to know about? We are in uncharted territory.

 

[Dr. B]

Read the rest.

If it's true, my guess is that the true cause of autoimmunity in these cases might be vitamin A deficiency. Since vitamin D makes the body use vitamin A, adding vitamin D exacerbates the problem by deepening the vitamin A deficiency.

The mechanism might be that vitamin A deficiency atrophies the adrenal glands, who have the role of secreting cortisone. Cortisone regulates the immune system.

All these imply that a high level of vitamin D without adequate vitamin A could be dangerous.

It is true but is it really safe to supplement both... or just stick to vitamin A from foods and any D from sunlight

I have had that experience. Didn't realize at first. 6000 units D for 6 months with no supplemental vitamin A or K2 resulted in what felt like, and was diagnosed as, osteoarthritis, very painful. Subsided completely on stopping vitamin D. Now take D (cholecalciferal 3000 IU in MCT on skin) and A (fish oil + retinyl palmitate gel caps,10,000 IU) and K2 (45mg menatetranone mixed into a fat), always all 3 (if any, but most days). Now D causes no problems.

K2 in physiological dose because dealing with fluoroquinolone (re)poisoning. Will back off to ~5mg/D after a while.

That (link, above, http://www.eurekalert.org/pub_releases/ ... 040809.php) is a VERY interesting article!

Do you still do this protocol? Those supplements and dosages can cause issues on their own even if the ratio of A and D and K seems balanced.

Those doses of K2 and A are megadoses and seem guaranteed to cause some sort of issues