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Vitamin D And Taurine As Actual Treatment For Many Cancers

  1. This study is a bit on the wild side in terms of effectiveness claims but it made it through peer reviews so I decided that it is worth posting. It also provides recommendations on optimal doses of these supplements commonly discussed on the forum. Apparently, the optimal dose of vitamin D is 400 IU daily and higher doses were actually harmful. The most effective dose for taurine was 175mg and it apparently it worked better than the 500mg dose. The optimal protocol for taurine was 175mg three times daily. People ingesting taurine not only had significantly lower oncogenic biomarkers but also significantly higher excretion of bacteria, viruses, fungi, heavy metals, and other toxic chemicals. So, taurine appears to be a pretty versatile substance and a chelator as well. What is also very interesting is that this study claims that majority of cancer patients had a viral infection with HPV-16, and undoubtedly the effectiveness of taurine as cancer treatment was at least partly due to the greatly reduced viral load as a result of supplementing with the amino acid. Even more interestingly, the official page from Cancer.gov seems to corroborate the findings of the study in regards to the causative link between HPV-16 and many cancers.
    HPV and Cancer

    Finally, the study is apparently with human patients so it makes even more relevant. If somebody can get the full article it would be very interesting to read and see some more specific information on these optimal doses as well why higher doses were detrimental.

    http://www.ingentaconnect.com/contentone/cog/aetr/2016/00000041/00000001/art00003
    Optimal Dose of Vitamin D3 400 I.U. for Average Adults has A Significant Anti-Cancer Effect, While Widely Used 2000 I.U. or Higher Promotes Cancer:... - PubMed - NCBI

    "...During the past 10 years, the author had found that the optimal dose of Vitamin D3 400 I.U. has safe & effective anticancer effects, while commonly used 2000∼5000 I.U. of Vit. D3 often creates a 2∼3 time increase in cancer markers. We examined the concentration of Taurine in normal internal organs and in cancer using Bi-Digital O–Ring Test. We found that Taurine levels in normal tissue are 4∼6ng. But, the amount of Taurine of average normal value of 5.0∼5.25ng was strikingly reduced to 0.0025∼0.0028ng in this study of several examples in adenocarcinomas of the esophagus, stomach, pancreas, colon, prostate, and lung, as well as breast cancer. The lowest Taurine levels of 0.0002∼0.0005ng were found in so called Zika virus infected babies from Brazil with microcephaly. While Vitamin D3 receptor stimulant 1α, 25 (OH)2D3 in normal tissues was 0.45∼0.53ng, they were reduced to 0.0025∼0.006ng in cancers (1/100th∼1/200th of normal value), particularly in various adenocarcinomas. All of these adenocarcinomas had about 1500ng HPV–16 viral infection. In 500 breast cancers, about 97% had HPV–16. The optimal dose of Taurine for average adult has been found to be about 175mg, rather than the widely used 500mg. In addition, since Taurine is markedly reduced to close to 1/1000th ∼ 1/2000th of its normal value in these cancer tissues, we examined the effect of the optimal dose of Taurine on cancer patients. Optimal dose of Taurine produced a very significant decrease in cancer–associated parameters, such as Oncogene C–fosAb2 & Integrin α5β1 being reduced to less than 1/1,000th, and 8–OH–dG (which increases in the presence of DNA mutation) reduced to less than 1/10th. The optimal dose of Taurine 175mg for average adult various cancer patient 3 times a day alone provide beneficial effects with very significant anti–cancer effects with strikingly increased urinary excretion of bacteria, viruses, & funguses, asbestos, toxic metals & other toxic substances. However, optimal doses of Taurine combined with optimal individualized doses of ω3 fish oil [EPA 180mg & DHA 120mg] & special cilantro tablet 3 times/day without creating harmful drug interactions among them including other essential drugs, is often extremely safe, more effective, economical & non–invasive new treatment for various cancer patients."
     
  2. there is something about vitamin d dosage , i recently think about comparision in animals and humans vitamin d level . i dont think any animal as hairless as humans ever go in direct sunlight as we go . maybe we should have cloths on us all the time , we just replaced out coat with cloths.

    i dont think animals have that much vitamin d as we humans get either from sun or heavy supplements. but ray also recommends vitamin d , so i think in future maybe we find out!

    taurine is widely used to treat cancer?! i didnt know that!

    and 175mg is optimal dose?! wow its interesting data.
     
  3. Taurine makes my stomach bloat and gassy, why is that? i just use pure powder
     
  4. apparently taurine is fermentable by bacteria, so maybe that causes it.
     
  5. Yeah, that study is quite interesting to say the least. The abstract makes it sound like they treated quite a few people but does not talk about survival and regression/progression of the tumors. If this is indeed legit, I think it will make quite a stir in the news.
     
  6. @paymanz yeah, so how can i go about it then? if i want to make use of Taurine?
     
  7. This. Also, taurine stimulates bile acid production and too much bile acids can irritate the colon. Finally, if taurine has bactericidal effect as the study above says that can lead to bloating due to massive die off and resultant endotoxin release. But it should subside as taurine improves the colon health and overall metabolism.
     
  8. Here it is...
     
  9. Wow, thanks! I will read and modify the post with some more detailed quotes.
     
  10. looks totally rubbish to me. I don't know where to start. But I think this is just junk.
     
  11. Any elaboration at all?
     
  12. This paragraph from the study seems really odd.. Same effect from holding the D3 as from ingesting it?

    . In just holding (In the clenched fist) the optimal dose of Vitamin D3 400 I.U., found Oncogene C-fosAb2 and Integrin α5β1 are decreased to less than 1/1000th of their values before treatment. We then had the patients consume this dose, and measured a cancerous area of the body 30 minutes later. The cancer markers showed a similar result as in the preliminary test of holding Vit. D3 400 I.U. When we gave the patients 2000~5000 I.U. Vit. D3 to hold in their clenched fist, Oncogene C-fosAb2 and Integrin α5β1 increase to 2~3 times their value. Then, we gave the patient Vit. D3 to ingest, and saw the same results, of a 2~3 times increase in Oncogene C-fosAb2 and Integrin α5β1, as when the patients held the dosage. Since these tests become repeatedly reproducible, we no longer give any dose that has an undesirable negative effect.

    Also, this doesnt sound too promising if true:

    If patients take the most commonly sold 500mg capsule of Taurine it is an undesirable overdose, and instead of producing an anti-cancer effect, cancer markers significantly increase


    I use several grams per day
     
  13. It seems to reference cites from the authors. Doesn't follow standard formats for methods and results. Seems to have a bunch of conclusions without cites or evidence.
     
  14. so the toxicity (d3) comes from the non optimal health from the liver and kidneys?
     
  15. More than 400 to 800 units of D3 supposedly increases "cancer markers" whatever that means. The 175 mg taurine increase excretion of microbes supposedly.
     
  16. Could glycine supplementation lead to the same thing?
     
  17. OK. I read this paper. I don't think that any information presented in the paper has any foundation in truth. This may seem harsh, but I think you will agree. Omura's paper Optimal Dose of Vitamin D3 400 I.U. for Average Adults has A Significant Anti-Cancer Effect, While Widely Used 2000 I.U. or Higher Promotes Cancer starts out with...
    This is true. The Serbian Professor Mihajlo Pupin at Columbia University filed a patent for wireless induction in the year 1900. Omura goes on...
    The 1st author mentioned is Omura himself. This sounds intriging...
    This is true. There is a patent for this, and it can be viewed here: Bi-digital O-ring test for imaging and diagnosis of internal organs of a patient. I read the patent and it seem absurd. Here are a few quotes from Omura's patent:
    I don't see how this could be very accurate. You might wonder what he used as a probe?
    And he goes on to abuse the word "image"...
    Except that he isn't actually imaging anything. He is performing voodoo. The only images of the cancerous organs are the ones in Omura's own head. Just in case you might think that I am misinterpreting this, here is a patent illustration:
    [​IMG]
    Yes. It really is that bad. He goes on, from the paper this time:
    He needs to warn people that the Wiki article is misleading and full of malice; just in case anyone actually decides to go there and search for this bizarre "imaging" technique.
    I don't think he can. It might be possible to remotely measure concentrations with resonance but I don't see how he can do this with a neon light and a finger test.
    Figures 2a to 8b are composed of photographs of stained tissue samples viewed under a light microscope. Every image has a URL from a different University. These do not appear to be his own samples. I can only imagine how he got the taurine and vitamin D concentrations.
    Somehow all breast cancer is composed of asbestos fibers. He uses cilantro and fish oil for this.
    He's Asian. He didn't have an editor for this paper either.
    Foot writing? Yes. You can see the piece of paper on page 49. This guy diagnoses cancer by the lines his patients draw with their toes.
    More evidence that he didn't have an editor. What he says about taurine seems to be true however. It can be synthesized by cysteine in the liver.
    [​IMG]
    He fills-up a few pages with boring case studies. He then says something quite bizarre:
    So Omura arrogates the ability to determine the amount of taurine in an infant from a photograph.
    Now he is pissing me off. He uses the unit nanograms about 100 times in this paper. You would think that he is referring to concentrations in some of his broken-English quotes such as this:
    But he never gives units for volume in the entire paper. You would expect to see ng/L on most of these measurements but you don't. I think most serious scientists would find this unacceptable. Not like it matters for imagined concentrations anyway; he could just as well say .5 unicorns or .00275 international voodoo units.

    Every single measurement in the paper lacks foundation IMO. I think the Vitamin D daily intake should be set 10x higher than 400IU.

    I also think that Omura is smoking something illicit.
     
  18. I would guess body hair density decreased as to create more vitamin d. No adaptation is accidental or purposeless.
     
  19. So you think humans need more vitamin d than animals and vitamin d has special functions in humans that are absent in animals?!
     
  20. This did get me thinking. Many animals can synthesize D in their fur and then ingest it through grooming. However, it seems that in some cases, exposure of UVB rays to fur increases endogenous D levels, even in absence of grooming. So fur and clothing may not be entirely comparable, although humans frequently have some skin exposed to direct sunlight, even when fully clothed.

    Vitamin D(3) synthesis in the entire skin surface of dairy cows despite hair coverage. - PubMed - NCBI
    "Hence, it appears that human clothing and cow hair are not comparable with respect to prevention of vitamin D(3) synthesis and that cows, like humans, synthesize vitamin D(3) evenly over their body surface. That vitamin D(3) should be synthesized from sebum on the hair and obtained by cows as a result of grooming is not supported by the findings in the present study either, because large differences were found between the treatment groups. If grooming were the source of vitamin D(3), then a relatively even 25(OH)D(3) concentration between treatments would be expected, because covered cows would obtain vitamin D(3) by grooming uncovered herdmates."

    Well, even different races of humans seem to have different requirements, but I don't know how the vitamin d requirements of humans, as a whole, compare to other animals.
     
  21. @Peater Piper

    haha that study is interesting.nice find.thanks!

    so animals without cover made 40ng/ml vitamin d.and it lowered in proportion to body surface coverage.

    i believe their fur blocks most of uvb , as you know uvb is not penetrating good. i think a normal clothing of humans in summer , a T-shirt gives us enough exposure to even make more than that.probably?!

    a light clothing blocks most of blue and UV light and lets red and IR light to pass.

    to me by looking at this study it seems like 40 ng/ml is around the optimal level. a level many experts also recommend.

    upload_2016-11-9_20-33-51.png

    and these animals make decent amount of retinol to balance that vitamin d . it can be really cool if we find data about how much retinol these animals can make a day!
     
  22. Probably, depending on time spent outside and latitude. My D went up to almost 40 during the summer just from going for 15-20 minute walks in the early afternoon wearing shorts and a t-shirt. Of course, I'm pretty pale, so I imagine I can make a fair amount of D in a short time. In the winter without supplementing my levels have dropped to 20, which is not so good.
     
  23. Great find Peater Piper.
     
  24. I started drank a red bull on Thursday and later that evening had a massive headache (I'm not prone to headaches, this was very unusual). Friday I drank another red bull, and had massive amount of gas. Woke up this morning feeling like I might be getting a cold. Before finding this post I thought to myself "it feels like die off." Good to know that's probably what it is.

    Though even with one red bull a day, the dosing is higher than this study. :/ I wonder if it would be better to sip half a red bull throuout the day :eh:
     
  25. Hey @tyw, not sure if you saw this thread but I would be interested in hearing your take on it. While the study is indeed bizarre it does have some very interesting points, including that dosing of substances should be based on metabolism and not body weight, as well as the contribution of various pathogens to cancer, and the therapeutic effects of vitamin D / taurine being tied to the increased amount of pathogens being excreted in urine. Sounds a bit similar to the TCM theory of disease.
     
  26. '
     
  27. No wonder I barely remember writing that, it had been written 360 days ago.

    But I did find an error in my previous comment:
    Point-five, or ½ unicorns actually equals 275·(10)⁻⁸ international voodoo units. It is .5 Unicorns—with big "U"—that equals .00275 IUᵥ. As with denoting energy in calories, the capital letter indicates kilo-units—i.e. one Unicorn equals 10³ unicorn (small "u"), or exactly ¹⁰⁄₆ imaginary Na⁺/K⁺-ATPase units.

    Rookie mistake.
     
  28. I think you would like to know that Mr. Omura has another interesting and bold "study". This time it is on treatment of ALS with MCT (caprylic acid).
    Caprylic acid in the effective treatment of intractable medical problems of frequent urination, incontinence, chronic upper respiratory infection, ... - PubMed - NCBI

    Hey @Amazoniac I think you will like it too. I just don't understand why this guy publishes on such Peatarian substances. This latest one uses caprylic acid, amoxicillin, cilantro, etc and he touts caprylic acid the most. If he had done a study on say estrogen or whole grains I would have dismissed him. But he just seems to throw in enough sense in his studies to catch my interest. If it wasn't for the whole "diagnosis by foot drawing" approach I think this guy could have published in much higher impact journals and actually gotten himself good attention.

    Can either one of you please try to get this study? I am interested in the dose he found most optimal for caprylic acid.
     
  29. another study, on chimps
    Relationship between sunlight exposure, housing condition, and serum vitamin D and related physiologic biomarker levels in captive chimpanzees (Pan... - PubMed - NCBI

    full text:
    http://www.ingentaconnect.com/content/aalas/cm/2007/00000057/00000004/art00010?crawler=true
    upload_2018-5-3_2-9-5.png
     
  30. Vitamin D: Physiology, Molecular Biology, and Clinical Applications (978-1-60327-300-8) - Michael Holick
    Chapter 59 - Anti-inflammatory Activity of Calcitriol That Contributes to Its Therapeutic and Chemopreventive Effects in Prostate Cancer

    "Our recent research has identified several new calcitriol target genes revealing novel molecular pathways of calcitriol action in prostate cells. The data suggest that calcitriol has anti-inflammatory actions that contribute to its anti-proliferative and cancer preventive effects in PCa. Calcitriol reduces both PG production (by suppressing COX-2 and increasing 15-PGDH expression) and PG biological actions (by PG receptor downregulation). We propose that calcitriol inhibition of the PG pathway contributes significantly to its anti-inflammatory actions. Combinations of calcitriol with NSAIDs exhibit synergistic enhancement of growth inhibition in PCa cell cultures suggesting that they may have therapeutic utility in PCa. The results of our recent clinical trial in patients with early recurrent PCa indicate that the combination of a weekly high-dose calcitriol with the non-selective NSAID naproxen has activity to slow the rate of rise of PSA in most patients. Another novel molecular pathway of calcitriol action involves the induction of MKP5 expression and the subsequent inhibition of p38 stress kinase signaling, resulting in the attenuation of the production of pro-inflammatory cytokines in prostate cells. There is also considerable evidence for an anti-inflammatory role for calcitriol in PCa through the inhibition of NF?B signaling in PCa cells. The discovery of these novel calcitriol-regulated pathways suggests that calcitriol has anti-inflammatory actions, in addition to its other anti-cancer effects, that may play an important role in the prevention and/or treatment of PCa."​

    @Obi-wan