Unsaturated Fats Role In Non-alcoholic Fatty Liver Disease

haidut

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So, @Makrosky and @ReSTART, check this out from another thread (courtesy of @paymanz). It is official information on IV nutrition, which says that PUFA (linoleic acid) is what causes NAFLD in up to 50% of patients on TPN, and of those up to 50% die.
More Evidence That Omega-3 Supplements Don't Work

"...Fatty liver is usually a more long term complication of TPN, though over a long enough course it is fairly common. The pathogenesis is due to using linoleic acid (an omega-6 fatty acid component of soybean oil) as a major source of calories.[10][11] TPN-associated liver disease strikes up to 50% of patients within 5–7 years, correlated with a mortality rate of 2–50%. Onset of this liver disease is the major complication that leads TPN patients to requiring an intestinal transplant.[12]
 

Makrosky

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So, @Makrosky and @ReSTART, check this out from another thread (courtesy of @paymanz). It is official information on IV nutrition, which says that PUFA (linoleic acid) is what causes NAFLD in up to 50% of patients on TPN, and of those up to 50% die.
More Evidence That Omega-3 Supplements Don't Work

"...Fatty liver is usually a more long term complication of TPN, though over a long enough course it is fairly common. The pathogenesis is due to using linoleic acid (an omega-6 fatty acid component of soybean oil) as a major source of calories.[10][11] TPN-associated liver disease strikes up to 50% of patients within 5–7 years, correlated with a mortality rate of 2–50%. Onset of this liver disease is the major complication that leads TPN patients to requiring an intestinal transplant.[12]
Thanks haidut!!
 

Dan Wich

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