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Tyronene + Tyromix + Pansterone Mixed Results

Discussion in 'Pharmaceutical Drugs' started by Bart1, Aug 1, 2018.

  1. Bart1

    Bart1 Member

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    Hi there,

    I'm about three months into peating, still learning everyday and came to the conclusion that I'm very hypothyroid. I first began implementing eating more peatlike, I felt a little bit better but I knew I had to start with thyroid. After a session with an endocrinologist who said there was nothing wrong with me I knew I had to start self medication.

    I started with Pansterone 4 drops topically. It improved my libido and energy a lot. I increased to 2x 4 drops a day but then I think a started to get some high cortisol symptoms, some weird cushing like things, a got a bit of a lump on the back of my neck, it feels thick and I got some achy pain under my armpits. I don't feel enlarged glands or anything but these are strange things, although I do remember this feeling from a couple of years ago.

    I went back to 4 drops Pansterone and started with Tyronene in the day and Tyromix in the evening. I felt very relaxed on Tyronene and also Tyromix, libido increased even more also better mood. I felt warmer and my heart rate increased a bit. The only thing now is that my sleeping which was already bad went worse. I wake up at night feels like high adrenaline. I take some milk with salt and honey but I still don't have a deep sleek and wake early with stress like symptoms.

    So it seems my cortisol problem is getting worse. I was under the impression that T3 should lower cortisol, as wel as pansterone. I increased my calorie intake, I feel I'm on the right path but something is not going well. Can somebody point me in the right direction ?
     
  2. James ardagna

    James ardagna Member

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    somewhere I think Peat says that t4 will lower adrenaline, however, thyroid hormone will make you more sensitive to adrenaline as the stress hormones over time give way to the supplemental thyroid as the driver of metabolism.
     
  3. ecstatichamster

    ecstatichamster Member

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    I think there is a transition period for this. For me, T3 and T4 didn’t help me until I had lowered my stored PUFAs through some episodes of no fat or very low fat.

    You might try waking up and taking a little T4 and T3 and going back to sleep.
     
  4. OP
    Bart1

    Bart1 Member

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    thanks for your replies. Indeed I was thinking the same thing, the body probably needs time to adjust to the new situation. I'm not that fat btw. I'm 1.86m and now I weigh about 79 kilo's. I was loosing quite some weight and I think muscle mass. It seem to stabilize now. I think I also lost a lot of water, due to increase of salt intake, I had some edema around my ankles. My liver health seems to improve as wel. Although sometimes when I take the pansterone I get a bit dizzy for a couple of minutes. Pregnonelone convert partly into Progesterone, which can convert in Cortisol, is that something I need to watch out for ?
     
  5. TripleOG

    TripleOG Member

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    You found success with topical or oral Tyronene/Tyromix?

    Things started falling into place when I lowered fat, cut starch, and stayed active. There was definitely a sensitivity to adrenaline when I first started messing with thyroid. Cup of salted OJ at bedside helped.
     
  6. James ardagna

    James ardagna Member

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    I think haidut has covered the topic of pregnenolone and its lowering effect on cortisol, or should I say normalising effect. the key is to realise that you are getting your body to switch from stress hormone driven metabolism to thyroid metabolism. this should be done slowly (Danny roddy has some good guidelines on his patreon site) as their will be adjustments for your body to make (such as being more sensitive to adrenaline and probably other hormones as well). things like coffee are good for your liver but will possibly drive adrenaline high until the thyroid metabolism takes over.
     
  7. OP
    Bart1

    Bart1 Member

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    I take it orally. currently 2 drops of tyronene during the day and in the evening 1 drop of Tyromix.

    I feel a bit stressed, but when I take tyronene I relax almost immediatly, temps and heart rate increase a bit.

    About Tyromix, my reserve T3 was in the upper reference range when I took a blood sample before I started with Tyromix. Could taking Tyromix with the T4 result in higher cortisol to block the extra T4 it is getting ?
     
  8. OP
    Bart1

    Bart1 Member

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    Yes you're absolutely right but it's a bit scary :( The last couple of weeks I seem to be losing muscle mass/weight. My muscles feel very spongy. I think this is my liver having trouble with managing insulin ? After my morning shake (OJ,Milk,Cane Sugar, Gelatin, Sugar, Salt) I feel that my muscle feed up a bit and that they have more volume but during the day it's gone. My skin feels very thin I can feel tendons. Maybe this is also because I lost some water retention ?
     
  9. Wagner83

    Wagner83 Member

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    You report high stress symptoms and the thin skin was recently described by haidut as a sign of high cortisol (transparent, too thin). I'd consider ditching the supplements and eating solid foods rather than liquid. Gelatin can be an issue as well. You're already quite low in kg, how much calories do you eat? Perhaps pushing metabolism when already really lean and underfed can be problematic.
     
  10. OP
    Bart1

    Bart1 Member

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    This is what I eat generally, but to be honest probably won't make this everyday, it's hard for me to get to 3000+ calories, unless I eat more fat and sugar... Should I add more sugar in my liquids ? Can I eat something solid like oats or buckwheat flakes , they have phyto estrogens right ?
     

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