Ras
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- Joined
- Sep 12, 2015
- Messages
- 931
Has anyone been able to try TUDCA and Taurine for a while and compare them?
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Has anyone been able to try TUDCA and Taurine for a while and compare them?
Thank you.I've been taking Taurine for well ove a year and started TUDCA a few weeks ago. TUDCA stimulates bile flow a lot better that Taurine in my experience. Taurine does it, but it's not as consistent and as pronounced as TUDCA. Not sure how its affecting liver numbers, dont have the money for tests at the moment, just relying on subjective experiences. Taurine is good for GABA though, better than TUDCA I'd say.
Thank you.
What benefits are you hoping to get from TUDCA?
From what I've read that's way, way too much for the average user. That dose was used on people with severe cirrohsis or some other pathological condition they were experimentally treating with TUDCA. For reducing ER stress and liver protection, 500mg/day is plenty, and 250mg/day would probably be fine.
I'm finding I'm actually getting a nice little boost out of TUDCA, and am wondering now if it doesn't work in much the same way as Ray says coffee works. And without the side effect of AChE inhibition that caffeine brings, that rattles some of us so much. I'm still looking into it and not sure if my fogbrain will be able to connect the dots, but if TUDCA turns out to be for me what I'm thinking it might, I might not have to worry about the demon coffee any more. That's a pretty big if at this point, but right now I'm encouraged. Only time will tell.
Also, I don't think TUDCA is something that should be taken long term. In some studies they've had people take it for up to a year but for everyday users it might be best to cycle it, like a couple months on, couple months off, or similar.
I want to say it has for me. Hair has stopped shedding..and not fatigued like before.Has anyone seen Thyroid improvements using TUDCA?
Anyone seen lab tests to prove it upregulates T3??
I have been using TUDCA at around 250mg the last couple of weeks.
This stuff makes you POOP!
I can't believe how often it makes you.
Im usually a once in the morning kind of guy, but this has ramped it up to like 3 times a day.
I have noticed energy increases from it as well. I feel like my workout performance is better and that my Urine colour is less dark than usual.
Overall, I think TUDCA is very therapeutic. I think it needs to be cycled, and also very low doses are probably still very good for liver support.
Yet again, learning so much from the Ray Peat forum. Thanks, everyone.
TUDCA is not much different than taurine when it comes to liver or metabolic effects, as it is in fact a taurine-conjugated bile acid. Taking taurine will stimulate its synthesis, as well as the synthesis of all other bile acids. All stimulators of bile acids or bile acids themselves will have a pro-metabolic effect as activating the bile acid receptor increases conversion of T4 into T3. That is how taurine helps diabetes, CVD, cholesterol, etc.
How Pregnenolone And Progesterone Raise Metabolism
How Taurine May Treat Diabetes
While it is interesting to experiment with, if you look at the animal studies that compared it to taurine you will see that it does not have that much more benefit to offer. Taurine has other benefits too that TUDCA does not - i.e. GABA agonism and decreasing catecholamines.
Does regular taurine have the same insulin sensitizing benefits if tudca?
Insulin sensitivity was increased in obese but non-diabetic men and women after 1,750mg daily ingestion of TUDCA for 4 weeks. Muscle and liver tissue became more insulin sensitive, but adipose (fat) tissue did not. The degree of improvement was approximately 30% improvement, which rivals current anti-diabetic pharmaceuticals such as thiazolinediones and metformin."
Tauroursodeoxycholic Acid - Scientific Review on Usage, Dosage, Side Effects | Examine.com
Were you able to improve your liver health meanwhile ?I have a feeling my liver isn't where it needs to be. I feel like utter crap if I drink a moderate amount of alcohol and I tend to benefit from Progesterone a lot, which along with other signs, tells me I have estrogen issues. I'm hoping improving liver function will help me not rely on Progesterone as much and also help my body function better overall.
An old question, but as I've been looking for the same and found an EU source (within EU, not UK) here it is: amazon.de:Where can one get TUDCA in Europe? From reputable company if possible.
"In an in vivo model, high-levelTaurine also upregulates the steroidgenic enzymes 3b-HSD and 17a-HSD, which are vital for the entire steroid cascade. TUDCA does none of these