Trying To Formulate An Alternative To Bluelene Without MB

[IROM]

I am trying to find resources on Mehtylene Blue and Gentian Violet derivatives that have higher antioxidant effects than either. Bluelene has patented use of Methylene Blue in cosmetics and while I doubt such a wide claim would hold up against my product which is multi-use (acne, facial detenser, anti-wrinkle etc.) I would like to look into the possibility of finding a BETTER alternative to MB.


Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia:
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia - PubMed

Any thoughts on Gentian Violet? Or the Azure B?

 

[IROM]

Sorry for double post: Found some interesting material on the MB actually being the "Prodrug" for MB derivative Azure B 's effects:

5. Is MB the prodrug of azure B (monodemethyl MB)?
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.476.2623&rep=rep1&type=pdf

I have decided to go with Azure B dye in my product but am looking for pure sources of this material.

 

[bluefish]

Stumbled on this post. Any luck so far?

 

[IROM]

I've shelved the project but pretty sure I developed a stable formula. Never got a good Azure B source. However, I've talked to several people who say that the moisturizer wouldn't break copyright because I have some different ingredients than the other product. Specifically using hyaluronic acid provides a stable long-term delivery via gel and there seems to be no breakdown in efficacy.