Triiodothyronine Supplementation For Hypothalamic Obesity


Jan 6, 2015
Patients with suprasellar lesions develop profound hypothalamic obesity and listlessness with no effective treatment. We added triiodothyronine (T(3)) supplementation in 3 such patients and present their response. All had previous nutritional counseling without benefit. All were treated for diabetes insipidus (DI) and hypopituitarism; serum free thyroxine (T(4)) level was normal. A 24-year-old woman (pineal tumor and astrocytoma) had weight gain (4.7 kg/yr for 3 years), cold intolerance, fatigue, dry skin, and constipation; after T(3), she lost 14 kg over 27 months and reported overall improvement. Her bone mineral density also improved. A 10.6-year-old boy (optic glioma) was gaining 6 kg/yr for 4 years; after T(3) supplement, he lost 4.3 kg over 11 months. A 12-year-old girl (mixed germ cell tumor) had weight gain (8.3 kg/yr for 3 years) and listlessness; after T(3), she lost 8.1 kg over 16 months and had improved alertness. All patients were asymptomatic despite supraphysiologic T(3) levels. We suggest that T(3) may serve as a simple and effective supplement, which can promote weight loss and improve the well being of these patients with hypothalamic obesity.
Similar threads
Thread starter Title Forum Replies Date
P Phosphate Supplementation Prevents A Decrease Of Triiodothyronine And Increases Resting Metabolic Ra Articles & Scientific Studies 0
P Serum Triiodothyronine Concentration And Na+,k(+)-atpase Activity In Liver And Skeletal Muscle Are I Articles & Scientific Studies 5
M Pregnenolone supplementation causing hairloss Pregnenolone 10
Advocate2021 Feedback on Thyroid Supplementation T4:T3 ratio 4:1 vs 3:1 Supplements, Pharmaceutical Drugs 0
Mito Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS D 0
metabolizm Vitamin D Supplementation is Improving my Sleep D 23
Velve921 Calcium Supplementation Supplements 4
Mito Vitamin D Supplementation During Winter: Effects On Stress Resilience D 10
A Long‐term Magnesium Supplementation Improves Glucocorticoid Metabolism Scientific Studies 0
P Testosterone Supplementation Help Male Issues 22
noqcks Supplementation For Multiple Sclerosis Ask For Help or Advice 15
F Can Thyroid Supplementation Lower Already Low Cortisol? Cortisol, Serotonin, Histamine 2
V Melatonin Supplementation Miscellaneous Health Discussions 2
GorillaHead Why Would Moderate Zinc Supplementation Cause Me To Develop Cystic Acne? Skin 14
metabolizm Magnesium Supplementation Ask For Help or Advice 16
S Fruit Supplementation Reduces Indices Of Exercise-induced Muscle Damage: A Systematic Review And Met Exercise 0
haidut Cardiolipin Supplementation May Reverse Signs Of Aging Scientific Studies 1
K Progesterone Supplementation Timing In Female Cycle Supplements, Pharmaceutical Drugs 4
S Symptoms Of Anemia Despite Iron Supplementation Female Issues 4
I Need Help With Thyroid Results And T4 Supplementation Synthetic Thyroid 34
zarrin77 Potassium Deficiency Makes Testosterone Plummet. Re-supplementation Restores It (rodent) Scientific Studies 33
B Pregnenolone Supplementation Supplements, Pharmaceutical Drugs 0
berk Vitamin B6 And Zinc And Supplementation Increase Conversion Of Tryptophan Into Serotonin Scientific Studies 8
H Elevated Levels Of Thiamine(B1) And B6 Without Supplementation Cause? Blood Work, Labs 6
Lenny Help And General Tips Wanted For Transdermal Supplementation Ask For Help or Advice 1
K Copper Supplementation Increased Brown Spots Number Minerals 56
L The Effects Of Vitamin D Supplementation On Thyroid Function In Hypothyroid Patients: A Randomized, Scientific Studies 3
berk Study: Tryptophan Supplementation Improves Body Composition Scientific Studies 0
GorillaHead Anyone Experience Eye Problems After Preworkout Supplementation? Eyes, Ears, Nose and Headaches/Migraines 0
Peatogenic Can Pregnenolone Supplementation Raise Cortisol? Pregnenolone 7
GorillaHead Once Again Mitochondrial Dysfunction At The Center Of AGING. Glycine Supplementation Huge Scientific Studies 5
Peatogenic Seeking Testimonials For Thyroid Supplementation And Skin Improvements Skin 2
P Occasional Boron Supplementation Minerals 162
Mito Effects Of Vitamin D Supplementation In Older Adults With Alzheimer's Disease: A Randomised, Double- D 5
Amazoniac Thyroxine Supplementation And The Length Needed For Stabilization Of Effects Thyroid and Hormones 1
Lokzo Urea Supplementation - Scientific Research Supplements, Pharmaceutical Drugs 6
haidut Supplementation With (long Chain) Saturated Fats Protects Liver From Alcohol Scientific Studies 1
P Thyroid Supplementation Ruined Me As A Man. How Can I Recover? Male Issues 39
Mito Effect Of High-Dose Vitamin D Supplementation On Volumetric Bone Density And Bone Strength D 1
P T3 Supplementation Vs Replacement Thyroid and Hormones 5
PleaseDoo21 What Is The General Consensus Of Boron Supplementation? Minerals 2
ddjd Which Co-factors For Vitamin D Supplementation? Ask For Help or Advice 10
Hans Omega 3 Supplementation Impairs Anti‐oxidant High‐density Lipoprotein Function Scientific Studies 0
A Magnesium Supplementation, Lowering Mood Ask For Help or Advice 24
B Can Autoimmune Hypothyroid Be Fixed Via Diet And Supplementation? Ask For Help or Advice 29
B Magnesium Supplementation Supplements, Pharmaceutical Drugs 22
shine Choline Supplementation Alleviates Fluoride-induced Testicular Toxicity By Restoring The NGF And MEK Scientific Studies 1
A What Is The Problem With High Dose Vitamin E Supplementation? E 11
H Pregnenolone Supplementation Safe For Endogenous Production ? Pregnenolone 15
Centsmom Insomnia With Thyroid Supplementation Insomnia, Sleep Issues 9

Similar threads