Triclosan is an endocrine disruptor

Mauritio

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Triclosan

--> Contained in toothpaste, deodorants, soaps and various textiles (often marketed as "allergy friendly")

-Lowers testosterone, pregnenolone, cholesterol LH and FSH

- Causes malformation of the testicles

- Decreases androgen receptor numbers and various steroidogenic enzymes (StAR,3bHSD,...)

- Women with the highest triclosan levels are less fertile



 
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Mauritio

Mauritio

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More extensive list of things containing triclosan:

Toothpaste.
Deodorants.
Cosmetics.
School supplies (pencils, calculators, scissors)
Plastic toys.
Cleaning supplies.
Laundry products,
clothing,
kitchenware,
furniture,
toys,
medical devices,
antibacterial soaps and body washes,
acne medications,
mouthwashes
wound disinfection solutions, and cosmetics. Triclosan is found in 75 percent of liquid hand soaps
 
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Mauritio

Mauritio

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"This decreased cAMP level resulted in the disruption of entire steroidogenic cascade causing a depressed synthesis of testosterone."

 
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Mauritio

Mauritio

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Triclosan is also associated with decreased male fertility:

"Elevated male urinary TCS concentrations were found to be associated with diminished fecundability. The risk of infertility significantly increased as TCS levels elevated."

 
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Mauritio

Mauritio

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Possible help of vitamin C and E against endocrine disruptor's effects.

"These observations suggest that vitamins C and E have ameliorative role against PCBs-induced testicular Leydig cells dysfunction."

 
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