Transdermal Vitamins (again. )

charlie

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Imagine that. Ray Peat right, again. :rockout
 

John Eels

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In plain English this means:
Vitamin A orally: 10'000 IU :arrow: Vitamin A topically: 50,000 IU

???
 

kettlebell

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John Eels said:
In plain English this means:
Vitamin A orally: 10'000 IU :arrow: Vitamin A topically: 50,000 IU

???

Correct.
He talks about the reasons why you on absorb 10-20% through your skin on in the Politics and Science second interview on Progesterone. I think its quite early on.
 

Ray-Z

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I was hoping for the opposite conclusion. After I apply A, D, & K topically, I feel like I've just finished jello wrestling. :lol:

But thanks for the useful info, Wilfrid & Kettlebell.
 

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John Eels

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I take fifteen drops of the Nutrisorb Vitamin A. It has happened many times that I spilled some of it on my jeans. I wonder how one takes like 40 drops. You're soaked in oil then. I prefer the lomi lomi massage.
 

Wilfrid

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John Eels said:
I take fifteen drops of the Nutrisorb Vitamin A. It has happened many times that I spilled some of it on my jeans. I wonder how one takes like 40 drops. You're soaked in oil then. I prefer the lomi lomi massage.

I had the same problem with the Nutrisorb....then I switched to the Biotics Research AE-Mulsion Forte which contains 12,500 UI in one drop.
Or you can use the Carlson's one (15000 UI in one softgel from palmitate.). This one do have safflower oil (a tiny amount) in it but as long as you use it on skin it's OK, just make sure you don't expose the area (where you put the vitamin A) to direct sunlight.
You can also rotate the area (in front of the neck, arms, thighs...) where you put your topical vitamins.
RP used 50000 UI of A, around 15000 UI of D, 2000 mg of K (from LEF super K2 complex, I think...) and around 100 UI of vitamin E....but those dosage are for RP, I don't have any idea to which dosage should be OK for the vast majority of us so I play safe and use only 25000 UI of A and a lot more of E and K( this one due to my IBD).
May be Cliff or orther's well informed can give us more accurate dosage for those vitamins....
 

Wilfrid

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What's interesting in the dosage RP used is that if we convert those amount to orally dosage it's almost what Chris Masterjohn think it's best to use for liposoluble vitamins (10000 UI of A, around 3000UI of D and a little bit more than 100mcg of K2).
 

Waga

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Johnwester130, in my case it's because my son (autistic) has a very damaged duodenum. Oral vitamins cause him pain.
 

Johnathan5544

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I just rubbed a few grams worth of vitamin e oil 80% alpha tocopherol on my skin. felt strong. if the vitamin e makes it into the blood then into the cells then it is by passing the alpha tocopherol transfer protein which makes the attp seem superfluous...
 

Johnathan5544

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where do you apply that is best absorb? And do you rub it till its gone?

Studies show the scrotum, and arm pits are the best absorbed place. after that fore head, and jaw line. i dont do it anymore. eating prawns is a good enough source of vitamin e (66mg per 100g).
 

Amazoniac

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Racialism is everywhere: say no to it.

- Racial differences in skin pathophysiology

"Maibach[22] applied C-labeled dipyrithione in different vehicles to stripped and unstripped skin of black and white volunteers and found 34% less absorption in blacks. A significantly lower penetration in blacks (47%) was also noted when a cosmetic vehicle (1:12:22:25:39 sodium lauryl sulfate, propylene glycol, stearyl alcohol, white petrolatum, distilled water) was compared with methyl alcohol on the forehead and when the methyl alcohol vehicle was compared with the shampoo vehicle on the scalp."

upload_2019-2-19_20-16-32.png

"A predisposition of blacks to "pomade acne" has been suggested,[24] This eruption, consisting mainly of comedones on the forehead and temporal area, seems to be a peculiar response of black skin to topical agents because this reaction can be detected in black children from 1 to 12 years of age.[46]"

"Kaidbey and Kligman[48] studied race-dependent cutaneous reactivity to topical coal.[48] There was a strikingly different response in the two groups; in whites, the response was primarily inflammatory, with development of papules and papulopustules in about 2 or 3 weeks; in blacks, the inflammatory response was largely absent, and, after about 14 days, an eruption of small open comedones appeared. The follicles of white subjects responded early, with rupture of the wall and outpouring of follicular contents in the dermis, whereas in blacks, the first response was proliferative with production and retention of horny cells. That is, in blacks, the skin reacts to a comedogenic compound with hyperkeratoses rather than with disintegration of follicles, suggesting a greater resistance to irritants."​

@haidut
 
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