Thoughts On 7-Keto DHEA

spudchick

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Mar 28, 2018
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Isn't 25mg, let alone 50mg, a huge dose even for a man? I thought the most recommended was like 5mg at a time?

It would be for DHEA but not for 7-Keto.

The lowest dose I've seen available at the usual online supplement sources is 25mg. IIRC they tested 7K at around 200mg daily (divided doses) without resulting any hormonal increases or (tmk) other side effects.
 
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Mossy

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Why don't you want androgen synthesis?
Some of the discussions on those threads are very pro-male; I was guessing she didn't want an excess, or male equivalency of androgens, as she stated with 7-keto she was able to avoid "...body hair or any other obvious hormonal effects."
 

Mossy

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Thanks for the links! Yes, I'm currently still taking it, though I tried omitting it for a little while as part of trying to get a handle on the best combinations with pregnenolone. I've had a mix of great physical and mental relief from pregnenolone but unfortunately also increased response to anxiety trigger situations (workplace)--it's like I haven't had adrenaline in my system in years, but I'm not handling. I found 7-keto after an undiagnosed crash that I believed to involve adrenal exhaustion. It helped then, but right now a difficult mix of weak adrenals, menopause and PTSD (childhood into adulthood, multiple trauma events) has got me where I'm really having problems with fatigue, seriously increased inflammantion/arthritis, horrible hot flashes, brain fog etc. and I wasn't having success with my usual regimen. In short, 7K helps but it has not been enough to handle this serious downward slide.

I've had good effect from some mild testosterone boosting herbs like Tribulus Terrestris so I'm not afraid of androgens (I think I was naturally very low in T most of my life) but I don't overdo it; I'm just searching for the right balance of things. For me.

The reason I thought pregnenolone might be helpful is this; the adrenals pick up the slack for the gonads in producing necessary whole body hormones after menopause, helping ease the transition. I felt perhaps I was deteriorating quickly due to the 'backup glands' not being capable of handling the job, and I read that pregnenolone is a raw material produced by the andrenals that can then be converted into other necessary hormones. It seemed like a good place to start.
No problem. Yeah, balancing hormones is really tough--I'm very new at it myself. I'd say you're further along than I am, as I've yet to take any consistently, due to the sporadic/unpredictable effects.

I'd say many on this forum are dealing with a situation similar to yours, myself included: sub-clinical (or clinical) symptoms of exhaustion, hormonal imbalance, and overall sub-optimal health (thyroid, liver, adrenals, G.I., etc,). These being the result of stress, with PTSD being the main culprit, in my opinion.

Yeah, as well, I've heard great things about pregnenolone, and that it would be the place to start--though, challenging to get things just right for each person. Good luck in your endeavor.
 

spudchick

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Thanks! I've been puttering with this for a long time, trying to keep my head above water with exactly what you describe. Docs have been little to no help. Unfortunately when they see a check next to "history of abuse" or see that I have PTSD, it' like you can see them mentally write me off--they stop bothering with diagnostic problem-solving and offer to prescribe antidepressants, and I learned quickly that those not only don't help but can actually make things much worse. I'm not going to them for mental health treatment, I'm going to them for wellness and to address the physical effects of both PTSD and what I suspect may be genetic deficiencies (I had stomach ulcers and measurable arthritic damage to some joints before I even reached high school). I'm not sure what kind of specialist might really be able to help me with this stuff. But I know that the few breakthroughs I've had have been keeping me together better than anything docs have offered to do.

Glad to have found this site, and I appreciate you pointing me to the pregnenolone links. Plenty of homework to do now!
 

Sofia

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Maybe someone knows if 7-keto DHEA acetate is safe? I do know that it is better to avoid pregnenolone acetate .
 

Nutritionist36

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Thanks for your response. But, yes, I do wonder if 7 keto is a very different issue. I have used it for many years at 50 mg daily with clear benefit to metabolism, cognition, lean muscle and as anti-inflammatory. Recently studying RP I decided to stop it as well as the 50 mg of normal DHEA I have taken daily for years. After about 6 weeks wash out I added back just 15 mg regular DHEA taken as 10 mg in morning and 5 mg in afternoon. This feels good but I still felt the distinct loss of the 7Keto DHEA so I added it back. It feels so important in its positive effects that I do not think I'll drop it again.
 

golder

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Thanks for your response. But, yes, I do wonder if 7 keto is a very different issue. I have used it for many years at 50 mg daily with clear benefit to metabolism, cognition, lean muscle and as anti-inflammatory. Recently studying RP I decided to stop it as well as the 50 mg of normal DHEA I have taken daily for years. After about 6 weeks wash out I added back just 15 mg regular DHEA taken as 10 mg in morning and 5 mg in afternoon. This feels good but I still felt the distinct loss of the 7Keto DHEA so I added it back. It feels so important in its positive effects that I do not think I'll drop it again.
Interesting. Do you still use it? I don't understand why people arent used keto DHEA over te normal one given that it is less likely to increase estrogen?
 

Brandin

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Really no one has any experience with the Supp?
I think ot could work well. I do not know if there are any long term downregulation of your own system tho. I am myself gonna start taking arimistane (suicidal ai simmilar to exemestane) and hope to see it lowering cortisol, increasing dht and lowering estrogen...

I think go for it if u got enough money to do blood test before after and during...
 

Brandin

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I think ot could work well. I do not know if there are any long term downregulation of your own system tho. I am myself gonna start taking arimistane (suicidal ai simmilar to exemestane) and hope to see it lowering cortisol, increasing dht and lowering estrogen...

I think go for it if u got enough money to do blood test before after and during...
This is the name: Androsta- 3,5-dien-7, 17-dione.

If the dht, preg, progest, dhea and exemestane were legal in sweden I would have opted for them but Androsta- 3,5-dien-7, 17-dione is perhaps the only legal one around here, and it seems promising...
 

ddjd

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Thanks for your response. But, yes, I do wonder if 7 keto is a very different issue. I have used it for many years at 50 mg daily with clear benefit to metabolism, cognition, lean muscle and as anti-inflammatory. Recently studying RP I decided to stop it as well as the 50 mg of normal DHEA I have taken daily for years. After about 6 weeks wash out I added back just 15 mg regular DHEA taken as 10 mg in morning and 5 mg in afternoon. This feels good but I still felt the distinct loss of the 7Keto DHEA so I added it back. It feels so important in its positive effects that I do not think I'll drop it again.
What did peat say to make you stop it??
 

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