If you have high serotonin like me, you must be careful or avoid these:
SJW, 5-htp and Sam-e - avoid them completely but you probably already know that!
Licorice - works wonders on peptic ulcers, the thyroid and lowers DHT but it has MAOI effect. Btw any suggestions for alternatives?
Hops - studies say it acts on serotonin but by itself I think I can tolerate it in low doses.
Yarrow (Achillea millefolium) - potentially boosts serotonin
Ginseng - boosts serotonin
Ashwaganda - made me more anxious and had hot waves. I think it's one of the reasons why my serotonin levels have become so high.
Gentiana - might boost serotonin
Chamomile and Peppermint - not sure if they act on serotonin or receptors but drinking a mixture of them after taking licorice triggered serotonin syndrome symptoms. By themselves however I can tolerate them.
Lavender - I can tolerate it but studies say it might bind to serotonin transporters (results showed that lavender essential oil and its main components exert affinity for the glutamate NMDA-receptor in a dose-dependent manner with an IC50 value of 0.04 μl/mL for lavender oil. In addition, lavender and linalool were also able to bind the serotonin transporter (SERT) whereas they did not show affinity for GABAA-benzodiazepine receptor.)
Apparently YMMV as in addition to being hyper serotonin I have a sluggish liver (undermethylator?) and I'm underweight. It's so hard for me to find herbs abd supplement that don't trigger a serotonin syndrome. Unfortunately I haven't found a Cyproheptadine-like herb or one that removes serotonin from the heart and brain.
SJW, 5-htp and Sam-e - avoid them completely but you probably already know that!
Licorice - works wonders on peptic ulcers, the thyroid and lowers DHT but it has MAOI effect. Btw any suggestions for alternatives?
Hops - studies say it acts on serotonin but by itself I think I can tolerate it in low doses.
Yarrow (Achillea millefolium) - potentially boosts serotonin
Ginseng - boosts serotonin
Ashwaganda - made me more anxious and had hot waves. I think it's one of the reasons why my serotonin levels have become so high.
Gentiana - might boost serotonin
Chamomile and Peppermint - not sure if they act on serotonin or receptors but drinking a mixture of them after taking licorice triggered serotonin syndrome symptoms. By themselves however I can tolerate them.
Lavender - I can tolerate it but studies say it might bind to serotonin transporters (results showed that lavender essential oil and its main components exert affinity for the glutamate NMDA-receptor in a dose-dependent manner with an IC50 value of 0.04 μl/mL for lavender oil. In addition, lavender and linalool were also able to bind the serotonin transporter (SERT) whereas they did not show affinity for GABAA-benzodiazepine receptor.)
Apparently YMMV as in addition to being hyper serotonin I have a sluggish liver (undermethylator?) and I'm underweight. It's so hard for me to find herbs abd supplement that don't trigger a serotonin syndrome. Unfortunately I haven't found a Cyproheptadine-like herb or one that removes serotonin from the heart and brain.