http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30431-5
The mantra of sugar makes you fat and causes diabetes has been bought into question. Those who carry the A variant of the Sweet-tooth Gene otherwise known as the FGF21 genotype, showed a preference for high-carb diets but were not overweight. It seems you may be able to eat all the sugar you want and not put on weight or get diabetes.
Apparently, the A variant of which encodes fibroblast growth factor 21, a hormone involved in alcohol and sugar consumption and insulin sensitization is a gene of interest by big pharma for weight loss. Unfortunately, it favours an apple shape which is associated with ill-health rather than the more preferred healthy pear shape. It favours more fat around the liver, pancreas and heart. Based on the Kempnar's Rice & sugar diet, we would beg to differ on this assumption.
Perhaps, as Ray has pointed out; the fat accumulation from excess carbs/sugar is likely to be saturated and thus protective. The researchers stated that the reason the high carb preference kept these people slim, was due to the reduction of protein and fat. McDougall's right. The reason we are fat and sick is because we eat like kings and queens. Too much protein and fats and oils together with too much carbs and sugar is more likely the recipe for poor health.
https://www.the-scientist.com/?arti...title/Sweet-Tooth-Gene-Tied-to-Less-Body-Fat/
Yet a new study of 451,000 people finds that the allele doesn’t universally mean poorer health. Researchers reported yesterday (April 10) in Cell Reports that those with the sweet-tooth variant actually have lower body fat than others, and no higher risk for type 2 diabetes. They did, however, find a link between the allele and high blood pressure and a thicker waistline.
Perhaps they had other unhealthy dietary and lifestye habits, however the fact they ate lower protein and fats, and a desire for fizzy drinks, coffee and alcohol, they were still protected and remained slim and no risk of diabetes or heart disease. I have not had a chance to read the complete paper as I am not a fan of GWAS research. Perhaps for those with the minor variant of this gene; being a little rotund around the waist is really not an issue.
“This goes against the current perception that eating sugar is bad for health. It may reduce body fat because the same allele also results in a lower consumption of protein and fat in the diet,” study coauthor Timothy Frayling, a molecular geneticist at the University of Exeter Medical School in the U.K., says in a press release. “But whilst this version of the gene lowers body fat, it also redistributes fat to the upper body, where it’s more likely to cause harm, including higher blood pressure.”
Their blood pressure is probably easily fixed by optimising their diet by including more mineral rich fruits and milk rather than fizzy drinks, coffee and alcohol.
According to Stephen Simpson, a nutrition researcher and director of the Charles Perkins Centre at Sydney University, they challenge the view that “no matter what, sugar consumption is bad. This villainisation needs proper exploration.”
As the rest of the world adopts a tax on sugar, Australia's stance is a clear: NO TAX on sugar.
Dozens of countries now tax sugary drinks but sweet-toothed Australia isn't interested
https://cosmosmagazine.com/biology/sweet-tooth-gene-shows-sugar-is-not-always-a-villain
I wonder how many of us on the RPF carry the minor SNP for this gene?
The mantra of sugar makes you fat and causes diabetes has been bought into question. Those who carry the A variant of the Sweet-tooth Gene otherwise known as the FGF21 genotype, showed a preference for high-carb diets but were not overweight. It seems you may be able to eat all the sugar you want and not put on weight or get diabetes.
Apparently, the A variant of which encodes fibroblast growth factor 21, a hormone involved in alcohol and sugar consumption and insulin sensitization is a gene of interest by big pharma for weight loss. Unfortunately, it favours an apple shape which is associated with ill-health rather than the more preferred healthy pear shape. It favours more fat around the liver, pancreas and heart. Based on the Kempnar's Rice & sugar diet, we would beg to differ on this assumption.
Perhaps, as Ray has pointed out; the fat accumulation from excess carbs/sugar is likely to be saturated and thus protective. The researchers stated that the reason the high carb preference kept these people slim, was due to the reduction of protein and fat. McDougall's right. The reason we are fat and sick is because we eat like kings and queens. Too much protein and fats and oils together with too much carbs and sugar is more likely the recipe for poor health.
https://www.the-scientist.com/?arti...title/Sweet-Tooth-Gene-Tied-to-Less-Body-Fat/
Yet a new study of 451,000 people finds that the allele doesn’t universally mean poorer health. Researchers reported yesterday (April 10) in Cell Reports that those with the sweet-tooth variant actually have lower body fat than others, and no higher risk for type 2 diabetes. They did, however, find a link between the allele and high blood pressure and a thicker waistline.
Perhaps they had other unhealthy dietary and lifestye habits, however the fact they ate lower protein and fats, and a desire for fizzy drinks, coffee and alcohol, they were still protected and remained slim and no risk of diabetes or heart disease. I have not had a chance to read the complete paper as I am not a fan of GWAS research. Perhaps for those with the minor variant of this gene; being a little rotund around the waist is really not an issue.
“This goes against the current perception that eating sugar is bad for health. It may reduce body fat because the same allele also results in a lower consumption of protein and fat in the diet,” study coauthor Timothy Frayling, a molecular geneticist at the University of Exeter Medical School in the U.K., says in a press release. “But whilst this version of the gene lowers body fat, it also redistributes fat to the upper body, where it’s more likely to cause harm, including higher blood pressure.”
Their blood pressure is probably easily fixed by optimising their diet by including more mineral rich fruits and milk rather than fizzy drinks, coffee and alcohol.
According to Stephen Simpson, a nutrition researcher and director of the Charles Perkins Centre at Sydney University, they challenge the view that “no matter what, sugar consumption is bad. This villainisation needs proper exploration.”
As the rest of the world adopts a tax on sugar, Australia's stance is a clear: NO TAX on sugar.
Dozens of countries now tax sugary drinks but sweet-toothed Australia isn't interested
https://cosmosmagazine.com/biology/sweet-tooth-gene-shows-sugar-is-not-always-a-villain
I wonder how many of us on the RPF carry the minor SNP for this gene?
