UG Krishnamurti
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- Sep 28, 2020
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This part is so interesting to me because it somehow aligns with the narrative and approach of Dr. Trevor Marshall [Excluding the VIT D part - of course XD].
So Trevor Marshall basically recommends using angiotensin II receptor blocker [OLMASARTAN] to raise and improve the innate immune system that will then fight of the pathogens in the body. He says that some people need to use it for 5-10 years or more.
In his view pathogens knock down the VDR [Vitamin D Receptor] which therefore allows these bugs to live inside the cells specifically without being attacked by the innate immune system. Poisoning the cells and the body.
Ray Peat said the following:
RP: "I’ve been studying inflammatory systems for a long time and in recent years I've been paying attention to the angiotensin system which used to be thought of as exclusively a matter of blood pressure regulation. And for many years there have been drugs to block angiotensin, reduce its formation, to lower blood pressure. But it happens that angiotensin is one of the things at the very root of the inflammatory process. Inflammation of various types can damage, for example, olfactory nerves [nerves for the sense of smell]. That is a very sensitive part of the nervous system. The Greeks considered the olfactory sense to be upon essential to understanding the essence of things. So the olfactory system fails under many different kinds of stresses, aging or poisoning - but the inflammatory system is one of the basic routes in cell damage. And this virus [COVID-19] attacks as a so-called receptor, causes its damage by binding to the ACE enzyme. ACE2 is one of the enzymes in the angiotensin blood pressure regulating system. But the enzyme that it binds to - ACE2 rather than ACE1 - is the enzyme that destroys angiotensin. The angiotensin is the mediator of inflammation. That will damage your particular type of cells. And ACE2 by destroying angiotensin protects against not only high blood pressure, but all types of inflammation. This is being studied in rheumatoid arthritis, degenerative osteoporosis, dementia, kidney and heart failure, especially lung fibrosis. Pulmonary arterial hypertension is an inflammatory process in the lungs, very highly influenced by angiotensin. So the lung damage caused by the virus is caused because it's knocking out our anti angiotensin virus???. So the logical approach to treating it is to restore that angiotensin enzyme. And all of the common anti inflammatory things, including the angiotensin receptor blockers and vitamin b1, aspirin and I think the t3 part of thyroid, progesterone and the several of the angiotensin receptor blockers all help to increase the production of the ACE2 enzyme that is knocked out by the virus. The virus lowers the availability of it. And these anti-inflammatory things restore the anti-inflammatory things. So even if the virus is there and you could produce more of the protective ACE2 enzyme then you are okay."
Q: Would the methylene blue help?
RP: "It works by keeping your Nitric Oxide down. Nitric oxide is turned on by angiotensin and so it works on at least part of the inflammatory system. And it also helps you maintain mitochondrial energy production and the failure of energy is at the deepest level of the inflammatory degenerative process.
I have heard a couple weeks ago a person in Italy said his friend was very sick in bed sleeping 21 hours a day and groggy and wondered what might help. I mentioned a Chinese research on losartan - an angiotensin receptor blocker - and the next day he said he had got a 50 milligram tablet of it, gave it to his friend and he said his friend was already out of bed, feeling okay. Then several days later he wrote again and said that his friend is exuberantly healthy and feels like he has new lungs. Vitamin D is known for quite a few years as a very reliable antiviral, anti-infective but it also increases at this anti-inflammatory enzyme along with progesterone, aspirin, and the anti serotonin drugs. That was the other best documented Chinese research. They were using an anti serotonin receptor blocker called cinanserin and having good results along with losartan."
Also - he recently said this:
Q: Hello Dr. Peat
What do you think of the "Innate immune system" and it's suppression and activation? Does it even exist and can you actually activate it or suppress it?
I hear a lot of doctors using angiotensin II receptor blockers like losartan and olmesartan just to name a few using it to improve innate immune response.
What is your take on it?
RP: Those do help; also quinine.
So Trevor Marshall basically recommends using angiotensin II receptor blocker [OLMASARTAN] to raise and improve the innate immune system that will then fight of the pathogens in the body. He says that some people need to use it for 5-10 years or more.
In his view pathogens knock down the VDR [Vitamin D Receptor] which therefore allows these bugs to live inside the cells specifically without being attacked by the innate immune system. Poisoning the cells and the body.
Ray Peat said the following:
RP: "I’ve been studying inflammatory systems for a long time and in recent years I've been paying attention to the angiotensin system which used to be thought of as exclusively a matter of blood pressure regulation. And for many years there have been drugs to block angiotensin, reduce its formation, to lower blood pressure. But it happens that angiotensin is one of the things at the very root of the inflammatory process. Inflammation of various types can damage, for example, olfactory nerves [nerves for the sense of smell]. That is a very sensitive part of the nervous system. The Greeks considered the olfactory sense to be upon essential to understanding the essence of things. So the olfactory system fails under many different kinds of stresses, aging or poisoning - but the inflammatory system is one of the basic routes in cell damage. And this virus [COVID-19] attacks as a so-called receptor, causes its damage by binding to the ACE enzyme. ACE2 is one of the enzymes in the angiotensin blood pressure regulating system. But the enzyme that it binds to - ACE2 rather than ACE1 - is the enzyme that destroys angiotensin. The angiotensin is the mediator of inflammation. That will damage your particular type of cells. And ACE2 by destroying angiotensin protects against not only high blood pressure, but all types of inflammation. This is being studied in rheumatoid arthritis, degenerative osteoporosis, dementia, kidney and heart failure, especially lung fibrosis. Pulmonary arterial hypertension is an inflammatory process in the lungs, very highly influenced by angiotensin. So the lung damage caused by the virus is caused because it's knocking out our anti angiotensin virus???. So the logical approach to treating it is to restore that angiotensin enzyme. And all of the common anti inflammatory things, including the angiotensin receptor blockers and vitamin b1, aspirin and I think the t3 part of thyroid, progesterone and the several of the angiotensin receptor blockers all help to increase the production of the ACE2 enzyme that is knocked out by the virus. The virus lowers the availability of it. And these anti-inflammatory things restore the anti-inflammatory things. So even if the virus is there and you could produce more of the protective ACE2 enzyme then you are okay."
Q: Would the methylene blue help?
RP: "It works by keeping your Nitric Oxide down. Nitric oxide is turned on by angiotensin and so it works on at least part of the inflammatory system. And it also helps you maintain mitochondrial energy production and the failure of energy is at the deepest level of the inflammatory degenerative process.
I have heard a couple weeks ago a person in Italy said his friend was very sick in bed sleeping 21 hours a day and groggy and wondered what might help. I mentioned a Chinese research on losartan - an angiotensin receptor blocker - and the next day he said he had got a 50 milligram tablet of it, gave it to his friend and he said his friend was already out of bed, feeling okay. Then several days later he wrote again and said that his friend is exuberantly healthy and feels like he has new lungs. Vitamin D is known for quite a few years as a very reliable antiviral, anti-infective but it also increases at this anti-inflammatory enzyme along with progesterone, aspirin, and the anti serotonin drugs. That was the other best documented Chinese research. They were using an anti serotonin receptor blocker called cinanserin and having good results along with losartan."
Also - he recently said this:
Q: Hello Dr. Peat
What do you think of the "Innate immune system" and it's suppression and activation? Does it even exist and can you actually activate it or suppress it?
I hear a lot of doctors using angiotensin II receptor blockers like losartan and olmesartan just to name a few using it to improve innate immune response.
What is your take on it?
RP: Those do help; also quinine.
