When any sort of endurance exercise is practiced, like running for example, or cycling, this stimulates an accelerated amount of lipolysis (beyond what's achieved at resting). So the more fat that is being liberated the more PUFA that's being liberated, naturally. But this typically isn't healthy for most people, or really any people. Some people are affected worse then other though. I remember before I gave up endurance exercises I would always have a massive stress response, and begin freezing in my hands and feet. It's probably best to limit lipolysis through omitting extra fat burning via intense exercise. Preferably also using things like aspirin and niacinamide to even further slow fat burning. The healthiest way to lose body fat is low and slow, which no fat person wants to hear, lol. But when you start eating these ketogenic diets and carnivore diets you really ramp up cortisol production which accelerates fat burning, thus causing an increase in PUFA burning as well.I was under the impression that fat tissue prefer to meet own energy needs by oxidizing saturated fat. This concentrates the PUFA in fat stores. But when you start to circulate the fat stores the PUFA is first to come out.