The Cause Of Baldness

[Elephanto]

@CLASH

It has shown efficacy against arthritis which is tissue calcification.
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. - PubMed - NCBI

It's a sulfur donor and sulfur has been shown to inhibit vascular calcification
Endogenous Sulfur Dioxide Inhibits Vascular Calcification in Association with the TGF-β/Smad Signaling Pathway

Peat wrote that inflammation leads to excessive uptake of calcium by cells, and MSM inhibits many inflammatory cytokines in a dose-dependent manner (NF-KB, IL-1, IL-6, TNF-Alpha, COX-2)
Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
Same article has study showing that it inhibits Nitric Oxide, and Nitric Oxide activates mast cells which induce calcification.
Association of mast cells with calcification in the human pineal gland. - PubMed - NCBI
Inhibits NLRP3 which induces calcification (mention of MSM inhibiting it is in the first article) :
Role of NLRP3 Inflammasomes in Atherosclerosis

Its range of effects is broad, but I don't know if it's simply sulfur doing all of that (although Taurine can increase NO while MSM has only been shown to inhibit it). In my experience, it's more efficient than Taurine.

 

[Arrade]

@Elephanto have you thought about using nattokinase or serrapatase to reduce fibrosis?
I already use natto for my arteries but was wondering if I should try serra concurrently if it makes a difference

 

[Elephanto]

@Elephanto have you thought about using nattokinase or serrapatase to reduce fibrosis?
I already use natto for my arteries but was wondering if I should try serra concurrently if it makes a difference

Yeah I put nattokinase as bookmark to buy eventually, looks interesting. Just to experiment and see if I can get the last bits of regrowth without getting back to detumescence. Serrapatase seems to have some suspicious side effects on the selfhaked page like skin inflammation that seem counterproductive to hair health, I'd have to lurk through pubmed and see what kind of mechanisms might explain it.

 

[Arrade]

Yeah I put nattokinase as bookmark to buy eventually, looks interesting. Just to experiment and see if I can get the last bits of regrowth without getting back to detumescence. Serrapatase seems to have some suspicious side effects on the selfhaked page like skin inflammation that seem counterproductive to hair health, I'd have to lurk through pubmed and see what kind of mechanisms might explain it.

Ah ok, thanks I wasn't aware.
Glad you're back on the forum, good to have interaction with someone so knowledgeable about this.

Started the acv rinse and scalp massages from PHH, gonna do all that everyday and dial down what supps I want.

 

[Elephanto]

@Arrade
No prob. You should also do this casually during the day :
Exercise Five - Shape Your Face
Triggering the occipitalis muscle, it moves your whole scalp. I don't see it as a main solution but something that will help and maintain your progress, since it's preventing calcification to settle again. Don't know what's PHH but make sure it's based on the chinese study technique. That is to press and create a pinch with both of your thumbs as you move them toward each other.

 

[Arrade]

@Arrade
No prob. You should also do this casually during the day :
Exercise Five - Shape Your Face
Triggering the occipitalis muscle, it moves your whole scalp. I don't see it as a main solution but something that will help and maintain your progress, since it's preventing calcification to settle again. Don't know what's PHH but make sure it's based on the chinese study technique. That is to press and create a pinch with both of your thumbs as you move them toward each other.

It's the perfect hair health method, it's 20 min massages with pinching, pressing, and stretching. Probably very similar
I think I may add the selenium and iodine to my vit stack considering my thyroid issues and it helps with fibrosis - I was actually going to fix my hypothyroid issues but think I need to cover hair first

 

[Elephanto]

It's the perfect hair health method, it's 20 min massages with pinching, pressing, and stretching. Probably very similar
I think I may add the selenium and iodine to my vit stack considering my thyroid issues and it helps with fibrosis - I was actually going to fix my hypothyroid issues but think I need to cover hair first

Yeah but it shouldn't be seen as two separate issues, this all-out attack on hair loss pretty much covers it, you'll find that many of the supps will help directly or indirectly with thyroid health. It's like an entry door to reach optimal general health but seen through the prism of hair health and with supps that specifically showed hair improvement results, instead of being lost and trying everything else that don't have shown positive testimonies. Then you can specialize into further testosterone, estrogen, dopamine/serotonin, thyroid optimization but the stack and habits like controlled breathing and avoidance advices already makes you progress in each. The only questionable one is high dose Iodine.

 

[Arrade]

Yeah but it shouldn't be seen as two separate issues, this all-out attack on hair loss pretty much covers it, you'll find that many of the supps will help directly or indirectly with thyroid health. It's like an entry door to reach optimal general health but seen through the prism of hair health and with supps that specifically showed hair improvement results, instead of being lost and trying everything else that don't have shown positive testimonies. Then you can specialize into further testosterone, estrogen, dopamine/serotonin, thyroid optimization but the stack and habits like controlled breathing and avoidance advices already makes you progress in each. The only questionable one is high dose Iodine.

What is the question/hesitation for the iodine?
https://jeffreydachmd.com/wp-conten...plementing-with-Iodine-Stephanie-Burst-ND.pdf
I was planning on using the iodine protocol to improve thyroid function overtime - one of my friends has seen results.
I do plan on specializing into thyroid -> testoterone and then healthiest diet possible, so our goals are similar.

Also, seperate question, is there any concerns of taking the vitamins at the same time? I.e. E and K can't be taken at the same time

 

[Elephanto]

@Arrade Peat claims that high dose Iodine can damage the thyroid, leading to hypothyroidism. ilikecat posted a bunch of studies that show this too (post #86) : Mega Dosing Iodine = Bad, Destroys Thyroid Tissue Permanently

In all cases it inhibits TSH which is inflammatory, so lowers inflammatory markers, and I think it has specific decalcifying properties too. Some people say they feel good on high dose, high temps etc so they likely didn't have a problem. One of the main reason it can be helpful is that a lot of people are high in Fluoride which calcifies the thyroid gland and inhibits Iodine uptake, but Boron (from the stack) has been shown to remove Fluoride and keep calcium in bones. In this case, it is probably a safer method to correct hypothyroidism along with moderate Iodine intake (like 100-200mcgs) or using Iodine drops only sporadically.

I'm not sure but I think E only antagonizes K1 absorption, though I did always take them apart to be sure. And again, not really from scientific proof, but I prefer to take only a few supps together instead of all at the same time, just to be sure I'm getting the most of them. Vit A should be taken with E. The fat soluble ones (A, E, K2) with meals or with a sip of coconut/olive oil; and the minerals if not taken with meals then with a sip of Apple Cider Vinegar except Mag Citrate, I prefer to take it apart in case it causes digestive issues.

 

[Arrade]

@Arrade Peat claims that high dose Iodine can damage the thyroid, leading to hypothyroidism. ilikecat posted a bunch of studies that show this too (post #86) : Mega Dosing Iodine = Bad, Destroys Thyroid Tissue Permanently

In all cases it inhibits TSH which is inflammatory, so lowers inflammatory markers, and I think it has specific decalcifying properties too. Some people say they feel good on high dose, high temps etc so they likely didn't have a problem. One of the main reason it can be helpful is that a lot of people are high in Fluoride which calcifies the thyroid gland and inhibits Iodine uptake, but Boron (from the stack) has been shown to remove Fluoride and keep calcium in bones. In this case, it is probably a safer method to correct hypothyroidism along with moderate Iodine intake (like 100-200mcgs) or using Iodine drops only sporadically.

I'm not sure but I think E only antagonizes K1 absorption, though I did always take them apart to be sure. And again, not really from scientific proof, but I prefer to take only a few supps together instead of all at the same time, just to be sure I'm getting the most of them. Vit A should be taken with E. The fat soluble ones (A, E, K2) with meals or with a sip of coconut/olive oil; and the minerals if not taken with meals then with a sip of Apple Cider Vinegar except Mag Citrate, I prefer to take it apart in case it causes digestive issues.

Hmm. I'll have to read more up on iodine then, definitely liked how I felt on 12.5 mg iodoral.
I've been reading that bodybuilding thread, thanks for plugging that.
This multi (great brand - Thorne) has a lot of what was listed:
https://www.amazon.com/Thorne-Resea...ltivitamin/dp/B0797HZ78W?ref=ast_p_pc_bs&th=1

 

[johnwester130]

What do you mean by 40%? Sounds like the results from a coerced "satisfaction" survey.

Cyclosporine A causes real, unequivocal hair growth in 94.6% of patients.

• Wysocki, G. P., and T. D. Daley. "Hypertrichosis in patients receiving cyclosporine therapy." Clinical and experimental dermatology 12.3 (1987): 191-196.
  • "Hypertrichosis is a cosmetically undesirable side-effect of cyclosporine therapy. A study of 56 insulin-depetident diabetics on long-term cyclosporine therapy indicated that unequivocal hypertrichosis occurred in 94.6% of the patients." ―Wysocki

Cyclosporine A is not thought to work on the androgen receptor. If androgens go against their natural hair stimulatory role on the scalp only, I could only guess that it's by inhibiting sebum—the classic and undeniable effect of androgens on the skin.

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The cortisol theory in the early days was confounded by a lack of understanding. The removal of the adrenal cortex causes undeniable hair growth in animals, while the removal of the adrenal medulla causes hair loss. The removal of of the entire gland can produce paradoxical results, depending on the animal and season.

• Stein, L., and E. Wertheimer. "Hair-loss as deficiency test of medullectomy in rats." Journal of Endocrinology 2.2 (1940): 418-427.
  • "Active hair-loss inhibiting preparations were obtained by extraction of fresh cattle adrenals with 0-2N HCl or with alcohol. The active principle was highly sensitive to oxygen and to alkali. [...] When cortex and medulla were separated as completely as possible, by far the predominant quantity of active principle was found in the medulla. The low activity noted for the cortex can probably be completely accounted for as due to the incomplete separation of cortex from medulla." ―Stein
  • "Medullectomy was carried out in part according to the method of Evans [1935/36], but generally according to a modification of this method, wherein one adrenal gland was completely removed, and the second adrenal was treated as indicated by Evans. [...] The operated animals showed largely the same course of hair-loss as did the adrenalectomized rats." ―Stein
  • "The hair-loss of medullectomized rats rose steeply to a maximum within 3-7 days of the operation, remained at the maximum for about a week, then fell sharply, though frequently still exceeded the normal maximum (20 mg.)" ―Stein
  • "Out of 17 medullectomized rats maintained under observation during prolonged time intervals, 13 developed distinct bald spots
  • "The effect of adrenalin on hair-loss: It has been pointed out that acid extract of adrenal medulla inhibits the hair-loss reaction of adrenalectomized rats." ―Stein
  • "In a subsequent series of experiments the effect of pure adrenalin rather than medulla extract was examined. Adrenalin was found to be markedly active. I-Adrenalin of Poulenc Frères was used." ―Stein
  • "Butcher & Richards [1939], working with rats, have shown that adrenalectomy strongly stimulates the growth of the second hair coat, previously inactive hair buds being found to show signs of development 40 hours after the operation. According to these authors, the effect is dependent on the removal of the adrenal cortex. It appears justified, therefore, in view of this and of our own findings, to conclude that hair-moult in rats is regulated by the adrenal glands." ―Stein
    • Butcher, Earl O., and R. A. Richards. "The relation of the adrenals to the retarded hair growth in underfed albino rats." Endocrinology25.5 (1939): 787-792.

It would seem pretty clear that adrenaline (epinephrine) from the adrenal medulla stimulates hair growth, while a product of the adrenal cortex—either aldosterone, cortisone, cortisol, dehydroepiandrosterone (or some combination thereof)—powerfully inhibits it.

The below article makes absolutely no mention of testosterone being produced by the adrenals (although Wikipedia claims "small amounts," less than 5% of total.)

• Rainey, William E., et al. "Dissecting human adrenal androgen production." Trends in Endocrinology & Metabolism 13.6 (2002): 234-239.

While it's true that castration prevents hair loss at an early age, castration after a certain age produces no such effect. If it was simply testosterone doing this, then any castration before the age of 30 would be be expected to have the same effect.

It has been conclusively shown—in more than one experiment—that during adolescence testosterone changes the hormonal profile of the adrenals. You could see this as an evolutionary advantage to provide males with more adrenal hormones. At Wimbleton and the French Open, men play 5 sets per match; women play three.

I think the only thing DHT has going for it is academic inertia, and nearly full endorsement from the media and pharmaceutical companies. Judging by how the AMA has treated some highly-effective historical cancer therapies—and some undeniable evidence pertaining to cardiovascular disease—you might be tempted to think that cures are not considered profitable by them, especially when pharmaceutical patents are still in force.

finasteride actually does interfere with cortisol in the body

The following reactions are known to be catalyzed by 5α-reductase:[9]

Deoxycorticosterone → 5α-Dihydrodeoxycorticosterone
Corticosterone → 5α-Dihydrocorticosterone
Cortisol → 5α-Dihydrocortisol

 

[Deleted member 5487]

This theory is probably the most valid I have come across. It all leads back to the gut.

Low chronic stress is the slow progression of baldness that appears in most men.

This higher sertonin/endo/cortisol starts the cascade that leads to=Low CO2/Low protective hormones/low thyroid=Bad Blood Flow=Calcification/Fibrosis

It also tends to calcify other extremities. Like the penis, Older/Balding men are more suseptable to ED. Then the doc throws them some super Nitrox Ox viagra

Baking Soda has been the best thing for my hair, maybe even showing regrowth, i believe this is because of both C02 as I get a strong libido reaction after consuming. But more importantly its "switching" the gut or killing off the bad bugs. As my cortisol/edma goes down after drinking.

Also every morning I have been eating 1-3 Tablespoons of liver patte cooked in a ton of butter, blended, and chilled. Also supplementing Zinc. This is providing the body with the nutrients to switch back to CO2
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By addressing the gut, you address all the down stem effects. Main stream medicine tries to tread blood flow(Rogan) or DHT (finasturide). Alternative theorys focus on massaging(blood flow) or Coconut oil/supplements lowering 5-AR which messing with allopregnenoloe.

So really the gut is the deciding factor

 

[Momado965]

Can baking soda be replaced by carbonated drinks?

 

[Deleted member 5487]

Can baking soda be replaced by carbonated drinks?

You can try, Doubtful to be as effective. These things also like coke/redbull contain citric and phosuric acids which leach calcium from the bones and calcify the soft tissues

Bakings soda PH effects are more important than the CO2: https://chrismasterjohnphd.com/blog/2017/08/16/measuring-urine-ph-got-love-working/

 

[rawmeat]

Baking Soda has been the best thing for my hair, maybe even showing regrowth, i believe this is because of both C02 as I get a strong libido reaction after consuming. But more importantly its "switching" the gut or killing off the bad bugs. As my cortisol/edma goes down after drinking.

How do you take baking soda? -- how many times/day and how much?

 

[Scenes]

This theory is probably the most valid I have come across. It all leads back to the gut.

Low chronic stress is the slow progression of baldness that appears in most men.

This higher sertonin/endo/cortisol starts the cascade that leads to=Low CO2/Low protective hormones/low thyroid=Bad Blood Flow=Calcification/Fibrosis

It also tends to calcify other extremities. Like the penis, Older/Balding men are more suseptable to ED. Then the doc throws them some super Nitrox Ox viagra

Baking Soda has been the best thing for my hair, maybe even showing regrowth, i believe this is because of both C02 as I get a strong libido reaction after consuming. But more importantly its "switching" the gut or killing off the bad bugs. As my cortisol/edma goes down after drinking.

Also every morning I have been eating 1-3 Tablespoons of liver patte cooked in a ton of butter, blended, and chilled. Also supplementing Zinc. This is providing the body with the nutrients to switch back to CO2
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------

By addressing the gut, you address all the down stem effects. Main stream medicine tries to tread blood flow(Rogan) or DHT (finasturide). Alternative theorys focus on massaging(blood flow) or Coconut oil/supplements lowering 5-AR which messing with allopregnenoloe.

So really the gut is the deciding factor

You keep changing your mind on this huh? Your last thread on hair was raving about gelatin.

 

[tallglass13]

finasteride actually does interfere with cortisol in the body

The following reactions are known to be catalyzed by 5α-reductase:[9]

Deoxycorticosterone → 5α-Dihydrodeoxycorticosterone
Corticosterone → 5α-Dihydrocorticosterone
Cortisol → 5α-Dihydrocortisol

Actually Finasteride , which is a modified Progestin, does not let progesterone go to cortisol. Normally, progesterone is able to go to cortisol if needed. But finasteride , since it is progesterone , does not go to cortisol. So it does effect cortisol somewhat.

 

[Deleted member 5487]

You keep changing your mind on this huh? Your last thread on hair was raving about gelatin.

No I keep learning and experimenting.

My stance on gelatin does not dissolve, it valuable protein devoid of tryptophan which sets of the serotonin-prolactin cascade.

 

[Inaut]

I think there’s something to baking soda @Amarsh213

I haven’t regrown hair besides tons of velus hairs but hair is much healthier/thicker and baking soda is one of the things I use daily

 

[Rjk]

@Amarsh213 how much of elephantos advice have you followed and how has your hair been doing?