Riesensackteil
Member
- Joined
- Apr 4, 2021
- Messages
- 499
Hello, I would like to compile links here about Caines and related stuff. I hope you can contribute. You can also add external links or Quotes if you want!
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
raypeatforum.com
KMUD: Aging and Energy Reversal (2013)
Raymond Peat, Ph.D. AGING AND ENERGY REVERSAL KMUD “Ask Your Herb Doctor” (2013) HD - Andrew Murray RP - Ray Peat HD: For those who just tuned in, could you give an outline of your academic and professional background? RP: In the sixties, I had been working in linguistics. But on my own...
Have You Tried Neural Therapy: Injecting Procaine Or Lidocaine
Here is Dr. Peat KMUD: Aging and Energy Reversal (2013) RP: And there is a little known branch of medicine. I think it was a German who originated it, I think it was called neural therapy, something like that, but it involved finding key points and injecting procaine or other local anesthetic...
Neural Excitation Deadly
In Harvard you learn something old everyday, main thing is to identify some gene expression while not saying anything about cortisol, gaba or NMDA. Despite all that, still relevant: Regulation of lifespan by neural excitation and REST. - PubMed - NCBI The mechanisms that extend lifespan in...
Benzocaine And -Caine Drugs
I just got some benzocaine 99+% purity powder in the mail from Amazon. I took a tiny crumb, probably 1/50th - 1/100th of a teaspoon. I felt some numbness in the throat for about 30 minutes to an hour, and feeling a pretty dramatic drop in stress. I'm feeling relaxed, a bit sleepy, breathing...
Antioxidant Effect Of Lidocaine And Procaine On Reactive Oxygen Species-induced Endothelial Dysfunct
Antioxidant effect of lidocaine and procaine on reactive oxygen species-induced endothelial dysfunction in the rabbit abdominal aorta Korean J Anesthesiol. 2010 Aug; 59(2): 104–110. Published online 2010 Aug 20. doi: 10.4097/kjae.2010.59.2.104 PMCID: PMC2926425 Antioxidant effect of lidocaine...
Procaine And Its Metabolites Increase CoA And Acetyl-coA Concentration In Various Tissues In Rats
I don't fully understand this one but it looks interesting and perhaps someone more knowledgeable would be able to explain it below? Z Alternsforsch. 1989 Jul-Aug;44(4):211-7. [Effect of procaine and procaine metabolites on coenzyme A and acetyl coenzyme A concentration in various tissues of...
Procaine Is A DNA-demethylating Agent With Growth-inhibitory Effects In Human Cancer Cells
We already knew this but I'm not sure we have this study. Abstract Methylation-associated silencing of tumor suppressor genes is recognized as being a molecular hallmark of human cancer. Unlike genetic alterations, changes in DNA methylation are potentially reversible. This possibility has...
Procaine Impairs The Function Of 5-HT3 Receptor-ion Channel Complex In Rat Sensory Ganglion Neurons
Previous studies have shown that local anesthetics block voltage-dependent Na+ channels and nicotinic acetylcholine receptors. The present study investigated the effect of the local anesthetic, procaine on another ligand-gated ion channel, the 5-HT3 receptor, in rat nodose ganglion neurons...
Lidocaine Demethylates DNA
Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro http://bja.oxfordjournals.org/content/early/2012/04/26/bja.aes128.full I wonder if chronic oral intake could reverse gene methylation.
Lidocaine Inhibits Collagen Accumulation (Fibrosis)
Collagen accumulates with aging and causes fibrosis. Although this study only highlights aged donors, it shows that lidocaine antagonizes the pro-fibrotic effects of IGF-1, TGF Beta-1, collagen proteins and inhibits collagen accumulation. Lidocaine impairs proliferative and biosynthetic...
Effect Of Lidocaine On Bone Matrix Formation By Osteoblasts
Effect of lidocaine on bone matrix formation by osteoblasts Effect of lidocaine on bone matrix formation by osteoblasts Srinivas Pentyala*, Emily Hughes, Pooja Mysore, Supriya Mishra, Julie Miller, Aleef Rahman and Kyle Urbanczyk Correspondence: Srinivas Pentyala...
Lidocaine Is Anti-bacterial And Anti-fungal, Synergistic With Aspirin And Anti-biotics
This study tests the anti-bacterial effect of Lidocaine and Aspirin . They had good antibiotic effects against all 10 tested bacteria ( in the first study) Here is a list of pathogens that lidocaine is effective against ( from the last study): C. albicans, E. coli,E. faecalis,H. influenzae, MRSA...
Lidocaine Inhibits Noradrenaline
Lidocaine inhibits noradrenaline release and shortens action potential durations. That's a great combination because heart failure patients have high noradrenaline levels and (generally) prolonged cardiac action potential. Propranolol and lidocaine inhibit neural norepinephrine release in...
Lidocaine Is An Endotoxin (TLR4) Antagonist
In this study, Lidocaine protects kidneys and liver from endotoxin by down-regulating TLR4 receptor. It's not antagonist at receptor, actually it downregulates the receptor which means a better mechanism. Lidocaine protects against renal and hepatic dysfunction in septic rats via downregulation...
Intranasal Lidocaine For Cluster Headaches
Cluster headache with ptosis responsive to intranasal lidocaine application: a case report. - PubMed - NCBI J Med Case Rep. 2012 Feb 15;6:64. doi: 10.1186/1752-1947-6-64. Cluster headache with ptosis responsive to intranasal lidocaine application: a case report. Bakbak B1, Gedik S, Koktekir...
Lidocaine Effect On Tnf Alpha And Nitrite After Endotoxin Exposure
Effect of inhaled and intravenous lidocaine on inflammatory reaction in endotoxaemic rats. - PubMed - NCBI Eur J Anaesthesiol. 2010 Jan;27(1):53-60. doi: 10.1097/EJA.0b013e32832b8a70. Effect of inhaled and intravenous lidocaine on inflammatory reaction in endotoxaemic rats. Flondor M1, Listle...
What's the rationale behind Ray Peat drinking lidocaine to cure colitis?
I found this quote from Ray Peat: "Ray: I had constantly bleeding colitis for more than a year, and when I took about 20 to 30 mg of lidocaine (in a 2% solution meant for oral, dental use) the symptoms stopped and haven’t returned in more than 30 years" What's the rational/mechanism behind...
Prolotherapy
Injecting a 50/50 mixture of dextrose and lidocaine into a joint, muscle, or cartilage. The theory behind it is that it sparks the body's anti-inflammatory responses by sparking inflammation. From an RP perspective, I would think that perhaps the lidocaine and dextrose lead to a direct...