lvysaur
Member
- Joined
- Mar 15, 2014
- Messages
- 2,286
The allele frequencies of fat-related SNPs almost always fit the following gradient:
African > Indian > European > Chinese > Thai > Siberian
If you're familiar w/me you know I make a lot of posts about genetics. I look at SNP databases just for fun sometimes, and over time I've realized that most fat-related SNPs follow a spectrum of African-Asian. A similar pattern emerges with TLR SNPs as well. I may make a separate thread for that.
(And btw "Chinese" includes Japan+Korea, "Thailand" = Southeast Asians, I just want to refrain from using verbose and vague directional terms like "East Asian" which can mean basically anything)
I'm not completely sure what is going on here, and I want to find out the nature of this difference, and evolutionary reasons for it. I will use this thread as a repository for posts about individual SNPs.
For those who don't know, gene =stretch of DNA. SNP = particular 1 letter spot. Allele = which letter that spot has
So the FADS1 gene determines various fat metabolism traits. An SNP on this gene is one single letter. The allele of this SNP is the "one or other" letter that it has: it can be a C (which links with a G on the mirror side), or it can be T (links with an A).
An allele frequency is simply the % people who have the allele in a given ethnicity or other population.
African > Indian > European > Chinese > Thai > Siberian
If you're familiar w/me you know I make a lot of posts about genetics. I look at SNP databases just for fun sometimes, and over time I've realized that most fat-related SNPs follow a spectrum of African-Asian. A similar pattern emerges with TLR SNPs as well. I may make a separate thread for that.
(And btw "Chinese" includes Japan+Korea, "Thailand" = Southeast Asians, I just want to refrain from using verbose and vague directional terms like "East Asian" which can mean basically anything)
I'm not completely sure what is going on here, and I want to find out the nature of this difference, and evolutionary reasons for it. I will use this thread as a repository for posts about individual SNPs.
For those who don't know, gene =stretch of DNA. SNP = particular 1 letter spot. Allele = which letter that spot has
So the FADS1 gene determines various fat metabolism traits. An SNP on this gene is one single letter. The allele of this SNP is the "one or other" letter that it has: it can be a C (which links with a G on the mirror side), or it can be T (links with an A).
An allele frequency is simply the % people who have the allele in a given ethnicity or other population.
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