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Priapism is caused by proerectile neurotransmission that can't be turned off. Either by increased nitrenergic neurotransmission (pde5 inhibitors) or antagonism of adrenergic system (Trazodone). I didn't find the numbers for priapism by Viagra just now but 1/6000 doesn't seem that bad. Maybe priapism caused anti-adrenergic medication is harder to treat as the antidote medication competes for the same receptors.@Aries
Tradozone can cause priapism due to it's anti-adrenergic qualities for example, but they claim only 1 of 6000 gets that, the priapism is claimed for clitoris also.
Priapism is caused by proerectile neurotransmission that can't be turned off. Either by increased nitrenergic neurotransmission (pde5 inhibitors) or antagonism of adrenergic system (Trazodone). I didn't find the numbers for priapism by Viagra just now but 1/6000 doesn't seem that bad. Maybe priapism caused anti-adrenergic medication is harder to treat as the antidote medication competes for the same receptors.
It seems likely that there would be a therapeutic window for ED for any substances that can cause priapism as it is not possible without proerectile transmission. Some people on TRT forums have used anti-adrenergic drugs in adjunction to nitric oxide stack but there are not a lot of research or anecdotes for their use in ED. They can also cause retrogade ejaculation.
I wonder if just fixing cold hands would also make a difference.
@redsun Right now, my attention / focus is divided in 3 areas:
I'll have to prioritize some supplements over another for budget reasons.
- sexual drive & libido
- energy levels
- mental state
As for the meat, I now eat 1 serving of meat / day. Much less than when I was Carnivore, and less than I usually ate over the past 2 years.
- Niacinamide: The B complex I have has Niacin in it, so I'll have to order this separately.
- Folic Acid. I have Folate, but as I understand, it's very different.
- Vitamin C: this one is cheap, are you talking about the standard Vit. C pills, right? Though I should be getting plenty from juice,s shouldn't I?
- Still, I will buy high-dose Vit. C tomorrow and start taking it
Keep in mind I am emphasizing B2 and folic acid specifically. Niacinamide will help as well. No need to do crazy doses of vitamin C, but you can take C, this is not going to be the determining part. High dose B2 and folic acid will be the determining part. This will help start back up nitric oxide and should start to remedy weak erections, and mentally I am sure it will help you when your erections improve. Meats provide lots of arginine, eggs or dairy provide very little keep this in mind. You want to input everything needed for NOS for maximal results.
B2 as plain riboflavin is the best and is very cheap and is the first thing I am recommending you get. If there is only room for one thing to get first, get B2. It usually comes in 100mg tablets. You can take 100mg once a day or, chop it up in half or into fourths and do 2x a day (breakfast, lunch) at 50mg or 25mg. Generally it is not recommended to take at night as some people get too stimulated by it. Helps a lot with energy personally for me as well as others who have used it B2 gets used up very quickly as it plays a role in activation of most of the other Bs. These high doses are very safe and very necessary to replete B2 stores as it takes time and consistency to build it back up but it should work quickly regardless.
@redsun do you think B2 inhibiting 5ar bad or is it not significant? I want to try B2 but worried about dht going lower.
Is folinic acid ok in place of folic acid? I know folate isn’t.
Might have to give it a try but also don't like how it can cause light sensitivity .The studies I believe were in vitro. According to haidut to in vivo studies did not show this.
Vitamin B2 (riboflavin) Is Endotoxin (LPS / TLR4) Antagonist
Might have to give it a try but also don't like how it can cause light sensitivity .
@redsun I got Vit C 1000 mg and Folic Acid 5mg. Will start taking it today.
Could not find B2 at the local pharmacies.
@GreekDemiGod That's great news, hope the effects continue.
10 - 15mg folic acid seems like a huge dose? Most folic acid I'm seeing is sold in 400mcg doses?